Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers
Purpose
This phase III trial studies how well gemcitabine hydrochloride and cisplatin given with or without nab-paclitaxel work in treating patients with newly diagnosed biliary tract cancers that have spread to other places in the body. Drugs used in chemotherapy, such as gemcitabine hydrochloride, cisplatin, and nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not known if giving gemcitabine hydrochloride and cisplatin with or without nab-paclitaxel may work better at treating biliary tract cancers.
Conditions
- Stage III Distal Bile Duct Cancer AJCC v8
- Stage III Gallbladder Cancer AJCC v8
- Stage III Intrahepatic Cholangiocarcinoma AJCC v8
- Stage IIIA Distal Bile Duct Cancer AJCC v8
- Stage IIIA Gallbladder Cancer AJCC v8
- Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8
- Stage IIIB Distal Bile Duct Cancer AJCC v8
- Stage IIIB Gallbladder Cancer AJCC v8
- Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8
- Stage IV Distal Bile Duct Cancer AJCC v8
- Stage IV Gallbladder Cancer AJCC v8
- Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
- Stage IVA Gallbladder Cancer AJCC v8
- Stage IVB Gallbladder Cancer AJCC v8
- Unresectable Extrahepatic Bile Duct Carcinoma
- Unresectable Gallbladder Carcinoma
- Unresectable Intrahepatic Cholangiocarcinoma
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Criteria
Inclusion Criteria:
- Patients must have histologically or cytologically confirmed intrahepatic
cholangiocarcinoma, extrahepatic cholangiocarcinoma, or gallbladder cancer
- NOTE: Pathology report must be uploaded in Rave. Histology report must be
consistent with an adenocarcinoma with pancreaticobiliary primary assuming there
are no pancreatic lesions and other primaries are ruled out per local standard
- Patients must have documented metastatic or locally advanced unresectable disease on
computed tomography (CT) or magnetic resonance (MR) imaging CT scans or MRIs used to
assess measurable disease. Must have been completed within 28 days prior to
registration. CT scans or MRIs used to assess non-measurable disease must have been
completed within 42 days prior to registration. All disease must be assessed and
documented on the Baseline Tumor Assessment Form
- Patient must not have a current diagnosis of ampullary cancer
- Patients must not have received prior systemic therapy for the current metastatic or
locally advanced biliary cancer
- Patient must not have received adjuvant therapy within 6 months prior to registration
- Patients must have a complete medical history and physical exam within 28 days prior
to registration
- Patients must have a Zubrod performance status of 0 or 1
- Patients must not have a history of peripheral neuropathy of grade 2 or greater by
Common Terminology Criteria for Adverse Events (CTCAE) 5.0. In CTCAE version 5.0 grade
2 sensory neuropathy is defined as ?moderate symptoms; limiting instrumental
activities of daily living (ADLs)?
- Absolute neutrophil count (ANC) >= 1,500/mcL (obtained within 28 days prior to
registration)
- Platelets >= 100,000/mcL (obtained within 28 days prior to registration)
- Hemoglobin >= 8 g/dL (obtained within 28 days prior to registration)
- Serum albumin >= 2.8 g/dL (obtained within 28 days prior to registration)
- Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (except patients
with Gilbert?s syndrome, who must have a direct bilirubin < 1.5 mg/dL) (obtained
within 28 days prior to registration)
- Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) and
serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) =< 8 x
IULN (obtained within 28 days prior to registration)
- Serum creatinine =< IULN OR calculated creatinine clearance >= 60 mL/min (obtained
within 28 days prior to registration)
- Patients must have CA19-9 obtained within 42 days prior to registration
- Patients must have sodium, potassium, bicarbonate, chloride, blood urea nitrogen
(BUN), calcium, total protein, magnesium, and alkaline phosphatase obtained within 28
days prior to registration
- Patients must not have an active infection requiring systemic therapy
- No other prior malignancy is allowed except for the following: adequately treated
basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated
stage I or II cancer from which the patient is currently in complete remission, or any
other cancer from which the patient has been disease free for two years
- Patients must not be pregnant or nursing. Women/men of reproductive potential must
have agreed to use an effective contraceptive method. A woman is considered to be of
"reproductive potential" if she has had menses at any time in the preceding 12
consecutive months. In addition to routine contraceptive methods, "effective
contraception" also includes heterosexual celibacy and surgery intended to prevent
pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy,
bilateral oophorectomy or bilateral tubal ligation. However, if at any point a
previously celibate patient chooses to become heterosexually active during the time
period for use of contraceptive measures outlined in the protocol, he/she is
responsible for beginning contraceptive measures
- Sites must seek additional patient consent for the future use of specimens
- Patients must be informed of the investigational nature of this study and must sign
and give written informed consent in accordance with institutional and federal
guidelines
- As a part of the Oncology Patient Enrollment Network (OPEN) registration process the
treating institution's identity is provided in order to ensure that the current
(within 365 days) date of institutional review board approval for this study has been
entered in the system
Study Design
- Phase
- Phase 3
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Arm I (nab-paclitaxel, cisplatin, gemcitabine hydrochloride) |
Patients receive nab-paclitaxel IV over 30 minutes, cisplatin IV over 60 minutes, and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. |
|
|
Experimental Arm II (cisplatin, gemcitabine hydrochloride) |
Patients receive cisplatin IV over 60 minutes and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. |
|
Recruiting Locations
Anchorage Associates in Radiation Medicine
Anchorage, Alaska 98508
Anchorage, Alaska 98508
Anchorage Radiation Therapy Center
Anchorage, Alaska 99504
Anchorage, Alaska 99504
Alaska Breast Care and Surgery LLC
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Alaska Oncology and Hematology LLC
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Alaska Women's Cancer Care
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Anchorage Oncology Centre
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Katmai Oncology Group
Anchorage, Alaska 99508
Anchorage, Alaska 99508
Providence Alaska Medical Center
Anchorage, Alaska 99508
Anchorage, Alaska 99508
CTCA at Western Regional Medical Center
Goodyear, Arizona 85338
Goodyear, Arizona 85338
Contact:
Site Public Contact
623-207-3000
Site Public Contact
623-207-3000
Kingman Regional Medical Center
Kingman, Arizona 86401
Kingman, Arizona 86401
Cancer Center at Saint Joseph's
Phoenix, Arizona 85004
Phoenix, Arizona 85004
Contact:
Site Public Contact
602-406-8222
Site Public Contact
602-406-8222
Mayo Clinic Hospital in Arizona
Phoenix, Arizona 85054
Phoenix, Arizona 85054
Contact:
Site Public Contact
855-776-0015
Site Public Contact
855-776-0015
Mayo Clinic in Arizona
Scottsdale, Arizona 85259
Scottsdale, Arizona 85259
Contact:
Site Public Contact
855-776-0015
Site Public Contact
855-776-0015
University of Arizona Cancer Center-Orange Grove Campus
Tucson, Arizona 85704
Tucson, Arizona 85704
Contact:
Site Public Contact
520-694-8900
Site Public Contact
520-694-8900
Banner University Medical Center - Tucson
Tucson, Arizona 85719
Tucson, Arizona 85719
University of Arizona Cancer Center-North Campus
Tucson, Arizona 85719
Tucson, Arizona 85719
Contact:
Site Public Contact
800-327-2873
Site Public Contact
800-327-2873
Mercy Hospital Fort Smith
Fort Smith, Arkansas 72903
Fort Smith, Arkansas 72903
Contact:
Site Public Contact
800-378-9373
Site Public Contact
800-378-9373
CHI Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas 71913
Hot Springs, Arkansas 71913
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas 72401
Jonesboro, Arkansas 72401
University of Arkansas for Medical Sciences
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
Contact:
Site Public Contact
501-686-8274
Site Public Contact
501-686-8274
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California 93420
Arroyo Grande, California 93420
PCR Oncology
Arroyo Grande, California 93420
Arroyo Grande, California 93420
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California 91505
Burbank, California 91505
Community Cancer Institute
Clovis, California 93611
Clovis, California 93611
Contact:
Site Public Contact
559-387-1827
Site Public Contact
559-387-1827
University Oncology Associates
Clovis, California 93611
Clovis, California 93611
Contact:
Site Public Contact
559-256-9680
Site Public Contact
559-256-9680
City of Hope Corona
Corona, California 92879
Corona, California 92879
City of Hope Comprehensive Cancer Center
Duarte, California 91010
Duarte, California 91010
Fremont - Rideout Cancer Center
Marysville, California 95901
Marysville, California 95901
Contact:
Site Public Contact
530-749-4400
Site Public Contact
530-749-4400
City of Hope Mission Hills
Mission Hills, California 91345
Mission Hills, California 91345
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California 92868
Orange, California 92868
Stanford Cancer Institute Palo Alto
Palo Alto, California 94304
Palo Alto, California 94304
University of California Davis Comprehensive Cancer Center
Sacramento, California 95817
Sacramento, California 95817
Contact:
Site Public Contact
916-734-3089
Site Public Contact
916-734-3089
Salinas Valley Memorial
Salinas, California 93901
Salinas, California 93901
UCSF Medical Center-Mission Bay
San Francisco, California 94158
San Francisco, California 94158
Contact:
Site Public Contact
877-827-3222
Site Public Contact
877-827-3222
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California 93401
San Luis Obispo, California 93401
City of Hope - Santa Clarita
Santa Clarita, California 91355
Santa Clarita, California 91355
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California 93444
Santa Maria, California 93444
City of Hope South Pasadena
South Pasadena, California 91030
South Pasadena, California 91030
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California 96161
Truckee, California 96161
Contact:
Site Public Contact
530-582-6450
Site Public Contact
530-582-6450
City of Hope Upland
Upland, California 91786
Upland, California 91786
City of Hope West Covina
West Covina, California 91790
West Covina, California 91790
Rocky Mountain Regional VA Medical Center
Aurora, Colorado 80045
Aurora, Colorado 80045
Contact:
Site Public Contact
888-336-8262
Site Public Contact
888-336-8262
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado 80907
Colorado Springs, Colorado 80907
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado 80907
Colorado Springs, Colorado 80907
Porter Adventist Hospital
Denver, Colorado 80210
Denver, Colorado 80210
Mercy Medical Center
Durango, Colorado 81301
Durango, Colorado 81301
Southwest Oncology PC
Durango, Colorado 81301
Durango, Colorado 81301
Saint Anthony Hospital
Lakewood, Colorado 80228
Lakewood, Colorado 80228
Littleton Adventist Hospital
Littleton, Colorado 80122
Littleton, Colorado 80122
Longmont United Hospital
Longmont, Colorado 80501
Longmont, Colorado 80501
Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado 80501
Longmont, Colorado 80501
Parker Adventist Hospital
Parker, Colorado 80138
Parker, Colorado 80138
Saint Mary Corwin Medical Center
Pueblo, Colorado 81004
Pueblo, Colorado 81004
Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut 06418
Derby, Connecticut 06418
Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut 06824
Fairfield, Connecticut 06824
Smilow Cancer Hospital Care Center - Guiford
Guilford, Connecticut 06437
Guilford, Connecticut 06437
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut 06105
Hartford, Connecticut 06105
Smilow Cancer Center/Yale-New Haven Hospital
New Haven, Connecticut 06510
New Haven, Connecticut 06510
Yale University
New Haven, Connecticut 06520
New Haven, Connecticut 06520
Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut 06473
North Haven, Connecticut 06473
Smilow Cancer Hospital-Orange Care Center
Orange, Connecticut 06477
Orange, Connecticut 06477
Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut 06790
Torrington, Connecticut 06790
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut 06611
Trumbull, Connecticut 06611
Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut 06708
Waterbury, Connecticut 06708
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut 06385
Waterford, Connecticut 06385
Beebe South Coastal Health Campus
Frankford, Delaware 19945
Frankford, Delaware 19945
Beebe Medical Center
Lewes, Delaware 19958
Lewes, Delaware 19958
Delaware Clinical and Laboratory Physicians PA
Newark, Delaware 19713
Newark, Delaware 19713
Helen F Graham Cancer Center
Newark, Delaware 19713
Newark, Delaware 19713
Medical Oncology Hematology Consultants PA
Newark, Delaware 19713
Newark, Delaware 19713
Christiana Care Health System-Christiana Hospital
Newark, Delaware 19718
Newark, Delaware 19718
Beebe Health Campus
Rehoboth Beach, Delaware 19971
Rehoboth Beach, Delaware 19971
TidalHealth Nanticoke / Allen Cancer Center
Seaford, Delaware 19973
Seaford, Delaware 19973
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware 19801
Wilmington, Delaware 19801
Sibley Memorial Hospital
Washington, District of Columbia 20016
Washington, District of Columbia 20016
AdventHealth Altamonte
Altamonte Springs, Florida 32701
Altamonte Springs, Florida 32701
Contact:
Site Public Contact
407-303-2200
Site Public Contact
407-303-2200
Mount Sinai Comprehensive Cancer Center at Aventura
Aventura, Florida 33180
Aventura, Florida 33180
AdventHealth Celebration
Celebration, Florida 34747
Celebration, Florida 34747
Contact:
Site Public Contact
407-303-4120
Site Public Contact
407-303-4120
Regional Cancer Center-Lee Memorial Health System
Fort Myers, Florida 33905
Fort Myers, Florida 33905
Mayo Clinic in Florida
Jacksonville, Florida 32224-9980
Jacksonville, Florida 32224-9980
Contact:
Site Public Contact
855-776-0015
Site Public Contact
855-776-0015
AdventHealth Kissimmee
Kissimmee, Florida 34744
Kissimmee, Florida 34744
Contact:
Site Public Contact
407-846-4343
Site Public Contact
407-846-4343
Mount Sinai Medical Center
Miami Beach, Florida 33140
Miami Beach, Florida 33140
AdventHealth Medical Group Urology at Orlando
Orlando, Florida 32803
Orlando, Florida 32803
Contact:
Site Public Contact
407-897-3499
Site Public Contact
407-897-3499
AdventHealth Orlando
Orlando, Florida 32803
Orlando, Florida 32803
AdventHealth East Orlando
Orlando, Florida 32822
Orlando, Florida 32822
Contact:
Site Public Contact
407-303-8110
Site Public Contact
407-303-8110
AdventHealth Winter Park
Winter Park, Florida 32792
Winter Park, Florida 32792
Contact:
Site Public Contact
407-646-7000
Site Public Contact
407-646-7000
Hawaii Cancer Care - Savio
'Aiea, Hawaii 96701
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-539-2273
Site Public Contact
808-539-2273
Pali Momi Medical Center
'Aiea, Hawaii 96701
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-486-6000
Site Public Contact
808-486-6000
Queen's Cancer Center - Pearlridge
'Aiea, Hawaii 96701
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-487-7447
Site Public Contact
808-487-7447
The Cancer Center of Hawaii-Pali Momi
'Aiea, Hawaii 96701
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-678-9000
Site Public Contact
808-678-9000
Hawaii Cancer Care Inc-POB II
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-524-6115
Site Public Contact
808-524-6115
Island Urology
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-532-0315
Site Public Contact
808-532-0315
Queen's Medical Center
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-545-8548
Site Public Contact
808-545-8548
Straub Clinic and Hospital
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-522-4333
Site Public Contact
808-522-4333
University of Hawaii Cancer Center
Honolulu, Hawaii 96813
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-586-2979
Site Public Contact
808-586-2979
Hawaii Cancer Care Inc-Liliha
Honolulu, Hawaii 96817
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-536-4888
Site Public Contact
808-536-4888
Kuakini Medical Center
Honolulu, Hawaii 96817
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-547-9816
Site Public Contact
808-547-9816
Queen's Cancer Center - Kuakini
Honolulu, Hawaii 96817
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-531-8521
Site Public Contact
808-531-8521
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii 96817
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-547-6881
Site Public Contact
808-547-6881
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii 96826
Honolulu, Hawaii 96826
Contact:
Site Public Contact
808-983-6090
Site Public Contact
808-983-6090
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii 96766
Lihue, Hawaii 96766
Contact:
Site Public Contact
808-535-7960
Site Public Contact
808-535-7960
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho 83706
Boise, Idaho 83706
Saint Luke's Mountain States Tumor Institute
Boise, Idaho 83712
Boise, Idaho 83712
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho 83605
Caldwell, Idaho 83605
Kootenai Medical Center
Coeur d'Alene, Idaho 83814
Coeur d'Alene, Idaho 83814
Walter Knox Memorial Hospital
Emmett, Idaho 83617
Emmett, Idaho 83617
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho 83619
Fruitland, Idaho 83619
Idaho Urologic Institute-Meridian
Meridian, Idaho 83642
Meridian, Idaho 83642
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho 83642
Meridian, Idaho 83642
Saint Alphonsus Medical Center-Nampa
Nampa, Idaho 83686
Nampa, Idaho 83686
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho 83686
Nampa, Idaho 83686
Kootenai Cancer Center
Post Falls, Idaho 83854
Post Falls, Idaho 83854
Kootenai Cancer Clinic
Sandpoint, Idaho 83864
Sandpoint, Idaho 83864
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho 83301
Twin Falls, Idaho 83301
Rush - Copley Medical Center
Aurora, Illinois 60504
Aurora, Illinois 60504
Illinois CancerCare-Bloomington
Bloomington, Illinois 61704
Bloomington, Illinois 61704
Illinois CancerCare-Canton
Canton, Illinois 61520
Canton, Illinois 61520
Memorial Hospital of Carbondale
Carbondale, Illinois 62902
Carbondale, Illinois 62902
SIH Cancer Institute
Carterville, Illinois 62918
Carterville, Illinois 62918
Illinois CancerCare-Carthage
Carthage, Illinois 62321
Carthage, Illinois 62321
Centralia Oncology Clinic
Centralia, Illinois 62801
Centralia, Illinois 62801
Northwestern University
Chicago, Illinois 60611
Chicago, Illinois 60611
University of Illinois
Chicago, Illinois 60612
Chicago, Illinois 60612
Contact:
Site Public Contact
312-355-3046
Site Public Contact
312-355-3046
Carle on Vermilion
Danville, Illinois 61832
Danville, Illinois 61832
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois 62526
Decatur, Illinois 62526
Decatur Memorial Hospital
Decatur, Illinois 62526
Decatur, Illinois 62526
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois 60115
DeKalb, Illinois 60115
Illinois CancerCare-Dixon
Dixon, Illinois 61021
Dixon, Illinois 61021
Contact:
Site Public Contact
815-285-7800
Site Public Contact
815-285-7800
Carle Physician Group-Effingham
Effingham, Illinois 62401
Effingham, Illinois 62401
Crossroads Cancer Center
Effingham, Illinois 62401
Effingham, Illinois 62401
Illinois CancerCare-Eureka
Eureka, Illinois 61530
Eureka, Illinois 61530
Illinois CancerCare-Galesburg
Galesburg, Illinois 61401
Galesburg, Illinois 61401
Western Illinois Cancer Treatment Center
Galesburg, Illinois 61401
Galesburg, Illinois 61401
Contact:
Site Public Contact
309-344-2831
Site Public Contact
309-344-2831
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois 60134
Geneva, Illinois 60134
Joliet Oncology-Hematology Associates Limited
Joliet, Illinois 60435
Joliet, Illinois 60435
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois 61443
Kewanee, Illinois 61443
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois 60045
Lake Forest, Illinois 60045
Illinois CancerCare-Macomb
Macomb, Illinois 61455
Macomb, Illinois 61455
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois 61938
Mattoon, Illinois 61938
Good Samaritan Regional Health Center
Mount Vernon, Illinois 62864
Mount Vernon, Illinois 62864
Contact:
Site Public Contact
618-242-4600
Site Public Contact
618-242-4600
Cancer Care Center of O'Fallon
O'Fallon, Illinois 62269
O'Fallon, Illinois 62269
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois 61350
Ottawa, Illinois 61350
Illinois CancerCare-Pekin
Pekin, Illinois 61554
Pekin, Illinois 61554
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Pekin, Illinois 61554
Pekin, Illinois 61554
Illinois CancerCare-Peoria
Peoria, Illinois 61615
Peoria, Illinois 61615
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois 61615
Peoria, Illinois 61615
Methodist Medical Center of Illinois
Peoria, Illinois 61636
Peoria, Illinois 61636
OSF Saint Francis Medical Center
Peoria, Illinois 61637
Peoria, Illinois 61637
Illinois CancerCare-Peru
Peru, Illinois 61354
Peru, Illinois 61354
Valley Radiation Oncology
Peru, Illinois 61354
Peru, Illinois 61354
Contact:
Site Public Contact
815-664-4141
Site Public Contact
815-664-4141
Illinois CancerCare-Princeton
Princeton, Illinois 61356
Princeton, Illinois 61356
Genesis Cancer Center - Silvis
Silvis, Illinois 61282
Silvis, Illinois 61282
Southern Illinois University School of Medicine
Springfield, Illinois 62702
Springfield, Illinois 62702
Contact:
Site Public Contact
217-545-7929
Site Public Contact
217-545-7929
Springfield Clinic
Springfield, Illinois 62702
Springfield, Illinois 62702
Contact:
Site Public Contact
800-444-7541
Site Public Contact
800-444-7541
Memorial Medical Center
Springfield, Illinois 62781
Springfield, Illinois 62781
Contact:
Site Public Contact
217-788-3528
Site Public Contact
217-788-3528
Carle Cancer Center
Urbana, Illinois 61801
Urbana, Illinois 61801
The Carle Foundation Hospital
Urbana, Illinois 61801
Urbana, Illinois 61801
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois 60555
Warrenville, Illinois 60555
Rush-Copley Healthcare Center
Yorkville, Illinois 60560
Yorkville, Illinois 60560
IU Health North Hospital
Carmel, Indiana 46032
Carmel, Indiana 46032
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana 46202
Indianapolis, Indiana 46202
Franciscan Health Indianapolis
Indianapolis, Indiana 46237
Indianapolis, Indiana 46237
Contact:
Site Public Contact
317-528-7060
Site Public Contact
317-528-7060
Franciscan Saint Elizabeth Health - Lafayette East
Lafayette, Indiana 47905
Lafayette, Indiana 47905
Woodland Cancer Care Center
Michigan City, Indiana 46360
Michigan City, Indiana 46360
Franciscan Health Mooresville
Mooresville, Indiana 46158
Mooresville, Indiana 46158
Contact:
Site Public Contact
317-834-3603
Site Public Contact
317-834-3603
Reid Health
Richmond, Indiana 47374
Richmond, Indiana 47374
Union Hospital
Terre Haute, Indiana 47804
Terre Haute, Indiana 47804
Contact:
Site Public Contact
812-238-7394
Site Public Contact
812-238-7394
Mary Greeley Medical Center
Ames, Iowa 50010
Ames, Iowa 50010
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
McFarland Clinic PC - Ames
Ames, Iowa 50010
Ames, Iowa 50010
McFarland Clinic PC-Boone
Boone, Iowa 50036
Boone, Iowa 50036
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa 50325
Clive, Iowa 50325
Mercy Cancer Center-West Lakes
Clive, Iowa 50325
Clive, Iowa 50325
Alegent Health Mercy Hospital
Council Bluffs, Iowa 51503
Council Bluffs, Iowa 51503
Greater Regional Medical Center
Creston, Iowa 50801
Creston, Iowa 50801
Genesis Medical Center - East Campus
Davenport, Iowa 52803
Davenport, Iowa 52803
Genesis Cancer Care Institute
Davenport, Iowa 52804
Davenport, Iowa 52804
Iowa Cancer Specialists
Davenport, Iowa 52807
Davenport, Iowa 52807
Iowa Methodist Medical Center
Des Moines, Iowa 50309
Des Moines, Iowa 50309
Contact:
Site Public Contact
515-241-6727
Site Public Contact
515-241-6727
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa 50309
Des Moines, Iowa 50309
Contact:
Site Public Contact
515-282-2921
Site Public Contact
515-282-2921
Broadlawns Medical Center
Des Moines, Iowa 50314
Des Moines, Iowa 50314
Contact:
Site Public Contact
515-282-2200
Site Public Contact
515-282-2200
Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa 50314
Des Moines, Iowa 50314
Mercy Medical Center - Des Moines
Des Moines, Iowa 50314
Des Moines, Iowa 50314
Iowa Lutheran Hospital
Des Moines, Iowa 50316
Des Moines, Iowa 50316
Contact:
Site Public Contact
515-241-8704
Site Public Contact
515-241-8704
McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa 50501
Fort Dodge, Iowa 50501
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
Trinity Regional Medical Center
Fort Dodge, Iowa 50501
Fort Dodge, Iowa 50501
Contact:
Site Public Contact
515-574-8302
Site Public Contact
515-574-8302
McFarland Clinic PC-Jefferson
Jefferson, Iowa 50129
Jefferson, Iowa 50129
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
McFarland Clinic PC-Marshalltown
Marshalltown, Iowa 50158
Marshalltown, Iowa 50158
Contact:
Site Public Contact
515-956-4132
Site Public Contact
515-956-4132
Siouxland Regional Cancer Center
Sioux City, Iowa 51101
Sioux City, Iowa 51101
Methodist West Hospital
West Des Moines, Iowa 50266-7700
West Des Moines, Iowa 50266-7700
Contact:
Site Public Contact
515-343-1000
Site Public Contact
515-343-1000
Mercy Medical Center-West Lakes
West Des Moines, Iowa 50266
West Des Moines, Iowa 50266
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas 67208
Wichita, Kansas 67208
Cancer Center of Kansas - Wichita
Wichita, Kansas 67214
Wichita, Kansas 67214
Flaget Memorial Hospital
Bardstown, Kentucky 40004
Bardstown, Kentucky 40004
Commonwealth Cancer Center-Corbin
Corbin, Kentucky 40701
Corbin, Kentucky 40701
Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky 40504
Lexington, Kentucky 40504
Saint Joseph Hospital East
Lexington, Kentucky 40509
Lexington, Kentucky 40509
Saint Joseph London
London, Kentucky 40741
London, Kentucky 40741
Jewish Hospital
Louisville, Kentucky 40202
Louisville, Kentucky 40202
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky 40202
Louisville, Kentucky 40202
Contact:
Site Public Contact
502-562-3429
Site Public Contact
502-562-3429
Saints Mary and Elizabeth Hospital
Louisville, Kentucky 40215
Louisville, Kentucky 40215
Jewish Hospital Medical Center Northeast
Louisville, Kentucky 40245
Louisville, Kentucky 40245
Jewish Hospital Medical Center South
Shepherdsville, Kentucky 40165
Shepherdsville, Kentucky 40165
LSU Health Baton Rouge-North Clinic
Baton Rouge, Louisiana 70805
Baton Rouge, Louisiana 70805
Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana 70809
Baton Rouge, Louisiana 70809
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana 70809
Baton Rouge, Louisiana 70809
Our Lady of the Lake Physicians Group - Medical Oncology
Baton Rouge, Louisiana 70809
Baton Rouge, Louisiana 70809
Medical Center of Baton Rouge
Baton Rouge, Louisiana 70816
Baton Rouge, Louisiana 70816
Ochsner High Grove
Baton Rouge, Louisiana 70836
Baton Rouge, Louisiana 70836
Ochsner Medical Center Jefferson
New Orleans, Louisiana 70121
New Orleans, Louisiana 70121
Harold Alfond Center for Cancer Care
Augusta, Maine 04330
Augusta, Maine 04330
Contact:
Site Public Contact
207-626-4855
Site Public Contact
207-626-4855
Eastern Maine Medical Center
Bangor, Maine 04401
Bangor, Maine 04401
Contact:
Site Public Contact
207-973-4274
Site Public Contact
207-973-4274
Waldo County General Hospital
Belfast, Maine 04915
Belfast, Maine 04915
Contact:
Site Public Contact
207-338-2500
Site Public Contact
207-338-2500
MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford
Biddeford, Maine 04005
Biddeford, Maine 04005
Lafayette Family Cancer Center-EMMC
Brewer, Maine 04412
Brewer, Maine 04412
Contact:
Site Public Contact
800-987-3005
Site Public Contact
800-987-3005
Stephens Memorial Hospital
Norway, Maine 04268
Norway, Maine 04268
Penobscot Bay Medical Center
Rockport, Maine 04856
Rockport, Maine 04856
MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford
Sanford, Maine 04073
Sanford, Maine 04073
Maine Medical Partners - South Portland
South Portland, Maine 04106
South Portland, Maine 04106
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland 21287
Baltimore, Maryland 21287
Dana-Farber Cancer Institute
Boston, Massachusetts 02215
Boston, Massachusetts 02215
Contact:
Site Public Contact
877-442-3324
Site Public Contact
877-442-3324
Lowell General Hospital
Lowell, Massachusetts 01854
Lowell, Massachusetts 01854
UMass Memorial Medical Center - University Campus
Worcester, Massachusetts 01655
Worcester, Massachusetts 01655
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan 48109
Ann Arbor, Michigan 48109
Contact:
Site Public Contact
800-865-1125
Site Public Contact
800-865-1125
Bronson Battle Creek
Battle Creek, Michigan 49017
Battle Creek, Michigan 49017
McLaren Cancer Institute-Bay City
Bay City, Michigan 48706
Bay City, Michigan 48706
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan 48183
Brownstown, Michigan 48183
McLaren Cancer Institute-Clarkston
Clarkston, Michigan 48346
Clarkston, Michigan 48346
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan 48038
Clinton Township, Michigan 48038
Henry Ford Medical Center-Fairlane
Dearborn, Michigan 48126
Dearborn, Michigan 48126
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan 48201
Detroit, Michigan 48201
Henry Ford Hospital
Detroit, Michigan 48202
Detroit, Michigan 48202
Weisberg Cancer Treatment Center
Farmington Hills, Michigan 48334
Farmington Hills, Michigan 48334
McLaren Cancer Institute-Flint
Flint, Michigan 48532
Flint, Michigan 48532
Singh and Arora Hematology Oncology PC
Flint, Michigan 48532
Flint, Michigan 48532
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan 49503
Grand Rapids, Michigan 49503
Mercy Health Saint Mary's
Grand Rapids, Michigan 49503
Grand Rapids, Michigan 49503
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan 49503
Grand Rapids, Michigan 49503
Allegiance Health
Jackson, Michigan 49201
Jackson, Michigan 49201
Bronson Methodist Hospital
Kalamazoo, Michigan 49007
Kalamazoo, Michigan 49007
West Michigan Cancer Center
Kalamazoo, Michigan 49007
Kalamazoo, Michigan 49007
Borgess Medical Center
Kalamazoo, Michigan 49048
Kalamazoo, Michigan 49048
McLaren-Greater Lansing
Lansing, Michigan 48910
Lansing, Michigan 48910
Mid-Michigan Physicians-Lansing
Lansing, Michigan 48912
Lansing, Michigan 48912
McLaren Cancer Institute-Lapeer Region
Lapeer, Michigan 48446
Lapeer, Michigan 48446
McLaren Cancer Institute-Macomb
Mount Clemens, Michigan 48043
Mount Clemens, Michigan 48043
McLaren Cancer Institute-Central Michigan
Mount Pleasant, Michigan 48858
Mount Pleasant, Michigan 48858
Mercy Health Mercy Campus
Muskegon, Michigan 49444
Muskegon, Michigan 49444
Lakeland Hospital Niles
Niles, Michigan 49120
Niles, Michigan 49120
Contact:
Site Public Contact
616-391-1230
Site Public Contact
616-391-1230
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan 49444
Norton Shores, Michigan 49444
Ascension Providence Hospitals - Novi
Novi, Michigan 48374
Novi, Michigan 48374
Henry Ford Medical Center-Columbus
Novi, Michigan 48377
Novi, Michigan 48377
McLaren-Port Huron
Port Huron, Michigan 48060
Port Huron, Michigan 48060
Spectrum Health Reed City Hospital
Reed City, Michigan 49677
Reed City, Michigan 49677
Lakeland Medical Center Saint Joseph
Saint Joseph, Michigan 49085
Saint Joseph, Michigan 49085
Marie Yeager Cancer Center
Saint Joseph, Michigan 49085
Saint Joseph, Michigan 49085
Henry Ford Macomb Health Center - Shelby Township
Shelby, Michigan 48315
Shelby, Michigan 48315
Ascension Providence Hospitals - Southfield
Southfield, Michigan 48075
Southfield, Michigan 48075
Munson Medical Center
Traverse City, Michigan 49684
Traverse City, Michigan 49684
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan 48322
West Bloomfield, Michigan 48322
Metro Health Hospital
Wyoming, Michigan 49519
Wyoming, Michigan 49519
Riverwood Healthcare Center
Aitkin, Minnesota 56431
Aitkin, Minnesota 56431
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota 56601
Bemidji, Minnesota 56601
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota 56401
Brainerd, Minnesota 56401
Fairview Ridges Hospital
Burnsville, Minnesota 55337
Burnsville, Minnesota 55337
Minnesota Oncology - Burnsville
Burnsville, Minnesota 55337
Burnsville, Minnesota 55337
Cambridge Medical Center
Cambridge, Minnesota 55008
Cambridge, Minnesota 55008
Mercy Hospital
Coon Rapids, Minnesota 55433
Coon Rapids, Minnesota 55433
Essentia Health - Deer River Clinic
Deer River, Minnesota 56636
Deer River, Minnesota 56636
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota 56501
Detroit Lakes, Minnesota 56501
Essentia Health Cancer Center
Duluth, Minnesota 55805
Duluth, Minnesota 55805
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota 55805
Duluth, Minnesota 55805
Miller-Dwan Hospital
Duluth, Minnesota 55805
Duluth, Minnesota 55805
Fairview Southdale Hospital
Edina, Minnesota 55435
Edina, Minnesota 55435
Lake Region Healthcare Corporation-Cancer Care
Fergus Falls, Minnesota 56537
Fergus Falls, Minnesota 56537
Essentia Health - Fosston
Fosston, Minnesota 56542
Fosston, Minnesota 56542
Unity Hospital
Fridley, Minnesota 55432
Fridley, Minnesota 55432
Essentia Health Hibbing Clinic
Hibbing, Minnesota 55746
Hibbing, Minnesota 55746
Contact:
Site Public Contact
218-786-3308
Site Public Contact
218-786-3308
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota 55369
Maple Grove, Minnesota 55369
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota 55109
Maplewood, Minnesota 55109
Saint John's Hospital - Healtheast
Maplewood, Minnesota 55109
Maplewood, Minnesota 55109
Abbott-Northwestern Hospital
Minneapolis, Minnesota 55407
Minneapolis, Minnesota 55407
Hennepin County Medical Center
Minneapolis, Minnesota 55415
Minneapolis, Minnesota 55415
Health Partners Inc
Minneapolis, Minnesota 55454
Minneapolis, Minnesota 55454
Monticello Cancer Center
Monticello, Minnesota 55362
Monticello, Minnesota 55362
New Ulm Medical Center
New Ulm, Minnesota 56073
New Ulm, Minnesota 56073
Essentia Health - Park Rapids
Park Rapids, Minnesota 56470
Park Rapids, Minnesota 56470
Fairview Northland Medical Center
Princeton, Minnesota 55371
Princeton, Minnesota 55371
North Memorial Medical Health Center
Robbinsdale, Minnesota 55422
Robbinsdale, Minnesota 55422
Mayo Clinic in Rochester
Rochester, Minnesota 55905
Rochester, Minnesota 55905
Contact:
Site Public Contact
855-776-0015
Site Public Contact
855-776-0015
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota 55416
Saint Louis Park, Minnesota 55416
Regions Hospital
Saint Paul, Minnesota 55101
Saint Paul, Minnesota 55101
United Hospital
Saint Paul, Minnesota 55102
Saint Paul, Minnesota 55102
Essentia Health Sandstone
Sandstone, Minnesota 55072
Sandstone, Minnesota 55072
Saint Francis Regional Medical Center
Shakopee, Minnesota 55379
Shakopee, Minnesota 55379
Lakeview Hospital
Stillwater, Minnesota 55082
Stillwater, Minnesota 55082
Sanford Thief River Falls Medical Center
Thief River Falls, Minnesota 56701
Thief River Falls, Minnesota 56701
Contact:
Site Public Contact
605-312-3320
Site Public Contact
605-312-3320
Essentia Health Virginia Clinic
Virginia, Minnesota 55792
Virginia, Minnesota 55792
Ridgeview Medical Center
Waconia, Minnesota 55387
Waconia, Minnesota 55387
Rice Memorial Hospital
Willmar, Minnesota 56201
Willmar, Minnesota 56201
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota 55125
Woodbury, Minnesota 55125
Sanford Cancer Center Worthington
Worthington, Minnesota 56187
Worthington, Minnesota 56187
Contact:
Site Public Contact
605-312-3320
Site Public Contact
605-312-3320
Fairview Lakes Medical Center
Wyoming, Minnesota 55092
Wyoming, Minnesota 55092
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus, Mississippi 39705
Columbus, Mississippi 39705
The West Clinic - Corinth
Corinth, Mississippi 38834
Corinth, Mississippi 38834
Baptist Cancer Center-Grenada
Grenada, Mississippi 38901
Grenada, Mississippi 38901
Baptist Memorial Hospital and Cancer Center-Union County
New Albany, Mississippi 38652
New Albany, Mississippi 38652
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi 38655
Oxford, Mississippi 38655
The West Clinic - Southaven
Southaven, Mississippi 38671
Southaven, Mississippi 38671
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven, Mississippi 38671
Southhaven, Mississippi 38671
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri 63011
Ballwin, Missouri 63011
Contact:
Site Public Contact
314-251-7058
Site Public Contact
314-251-7058
Saint Francis Medical Center
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
Southeast Cancer Center
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
Contact:
Site Public Contact
573-651-5550
Site Public Contact
573-651-5550
Saint Luke's Hospital
Chesterfield, Missouri 63017
Chesterfield, Missouri 63017
Contact:
Site Public Contact
314-205-6936
Site Public Contact
314-205-6936
Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri 63141
Creve Coeur, Missouri 63141
Parkland Health Center - Farmington
Farmington, Missouri 63640
Farmington, Missouri 63640
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Capital Region Southwest Campus
Jefferson City, Missouri 65109
Jefferson City, Missouri 65109
Freeman Health System
Joplin, Missouri 64804
Joplin, Missouri 64804
Mercy Hospital Joplin
Joplin, Missouri 64804
Joplin, Missouri 64804
Delbert Day Cancer Institute at PCRMC
Rolla, Missouri 65401
Rolla, Missouri 65401
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri 65401
Rolla, Missouri 65401
Contact:
Site Public Contact
573-458-6379
Site Public Contact
573-458-6379
Heartland Regional Medical Center
Saint Joseph, Missouri 64506
Saint Joseph, Missouri 64506
Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri 63109
Saint Louis, Missouri 63109
Contact:
Site Public Contact
314-353-1870
Site Public Contact
314-353-1870
Washington University School of Medicine
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
Siteman Cancer Center-South County
Saint Louis, Missouri 63129
Saint Louis, Missouri 63129
Missouri Baptist Medical Center
Saint Louis, Missouri 63131
Saint Louis, Missouri 63131
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Siteman Cancer Center at Christian Hospital
Saint Louis, Missouri 63136
Saint Louis, Missouri 63136
Mercy Hospital Saint Louis
Saint Louis, Missouri 63141
Saint Louis, Missouri 63141
Contact:
Site Public Contact
314-251-7066
Site Public Contact
314-251-7066
Siteman Cancer Center at Saint Peters Hospital
Saint Peters, Missouri 63376
Saint Peters, Missouri 63376
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri 63670
Sainte Genevieve, Missouri 63670
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Mercy Hospital Springfield
Springfield, Missouri 65804
Springfield, Missouri 65804
Contact:
Site Public Contact
417-269-4520
Site Public Contact
417-269-4520
CoxHealth South Hospital
Springfield, Missouri 65807
Springfield, Missouri 65807
Contact:
Site Public Contact
417-269-4520
Site Public Contact
417-269-4520
Missouri Baptist Sullivan Hospital
Sullivan, Missouri 63080
Sullivan, Missouri 63080
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, Missouri 63127
Sunset Hills, Missouri 63127
Contact:
Site Public Contact
314-996-5569
Site Public Contact
314-996-5569
Mercy Hospital Washington
Washington, Missouri 63090
Washington, Missouri 63090
Contact:
Site Public Contact
636-390-1600
Site Public Contact
636-390-1600
Community Hospital of Anaconda
Anaconda, Montana 59711
Anaconda, Montana 59711
Billings Clinic Cancer Center
Billings, Montana 59101
Billings, Montana 59101
Bozeman Deaconess Hospital
Bozeman, Montana 59715
Bozeman, Montana 59715
Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana 59405
Great Falls, Montana 59405
Great Falls Clinic
Great Falls, Montana 59405
Great Falls, Montana 59405
Kalispell Regional Medical Center
Kalispell, Montana 59901
Kalispell, Montana 59901
Saint Patrick Hospital - Community Hospital
Missoula, Montana 59802
Missoula, Montana 59802
Community Medical Hospital
Missoula, Montana 59804
Missoula, Montana 59804
CHI Health Saint Francis
Grand Island, Nebraska 68803
Grand Island, Nebraska 68803
CHI Health Good Samaritan
Kearney, Nebraska 68847
Kearney, Nebraska 68847
Saint Elizabeth Regional Medical Center
Lincoln, Nebraska 68510
Lincoln, Nebraska 68510
Nebraska Methodist Hospital
Omaha, Nebraska 68114
Omaha, Nebraska 68114
Contact:
Site Public Contact
402-354-5144
Site Public Contact
402-354-5144
Alegent Health Immanuel Medical Center
Omaha, Nebraska 68122
Omaha, Nebraska 68122
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska 68124
Omaha, Nebraska 68124
Alegent Health Lakeside Hospital
Omaha, Nebraska 68130
Omaha, Nebraska 68130
Creighton University Medical Center
Omaha, Nebraska 68131
Omaha, Nebraska 68131
Midlands Community Hospital
Papillion, Nebraska 68046
Papillion, Nebraska 68046
Carson Tahoe Regional Medical Center
Carson City, Nevada 89703
Carson City, Nevada 89703
Cancer and Blood Specialists-Henderson
Henderson, Nevada 89052
Henderson, Nevada 89052
Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada 89052
Henderson, Nevada 89052
Comprehensive Cancer Centers of Nevada-Horizon Ridge
Henderson, Nevada 89052
Henderson, Nevada 89052
Las Vegas Cancer Center-Henderson
Henderson, Nevada 89052
Henderson, Nevada 89052
OptumCare Cancer Care at Seven Hills
Henderson, Nevada 89052
Henderson, Nevada 89052
21st Century Oncology-Henderson
Henderson, Nevada 89074
Henderson, Nevada 89074
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson, Nevada 89074
Henderson, Nevada 89074
Las Vegas Urology - Green Valley
Henderson, Nevada 89074
Henderson, Nevada 89074
Urology Specialists of Nevada - Green Valley
Henderson, Nevada 89074
Henderson, Nevada 89074
Desert West Surgery
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
OptumCare Cancer Care at Oakey
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
University Medical Center of Southern Nevada
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
Hope Cancer Care of Nevada
Las Vegas, Nevada 89103
Las Vegas, Nevada 89103
Urology Specialists of Nevada - Central
Las Vegas, Nevada 89106
Las Vegas, Nevada 89106
21st Century Oncology
Las Vegas, Nevada 89109
Las Vegas, Nevada 89109
Sunrise Hospital and Medical Center
Las Vegas, Nevada 89109
Las Vegas, Nevada 89109
Las Vegas Prostate Cancer Center
Las Vegas, Nevada 89113
Las Vegas, Nevada 89113
21st Century Oncology-Vegas Tenaya
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Las Vegas Urology - Cathedral Rock
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Las Vegas Urology - Smoke Ranch
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
OptumCare Cancer Care at MountainView
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Urology Specialists of Nevada - Northwest
Las Vegas, Nevada 89128
Las Vegas, Nevada 89128
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada 89135
Las Vegas, Nevada 89135
Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas, Nevada 89144
Las Vegas, Nevada 89144
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas, Nevada 89144
Las Vegas, Nevada 89144
Summerlin Hospital Medical Center
Las Vegas, Nevada 89144
Las Vegas, Nevada 89144
Las Vegas Cancer Center-Medical Center
Las Vegas, Nevada 89148-2405
Las Vegas, Nevada 89148-2405
21st Century Oncology-Fort Apache
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
Urology Specialists of Nevada - Southwest
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada 89169
Las Vegas, Nevada 89169
University Cancer Center
Las Vegas, Nevada 89169
Las Vegas, Nevada 89169
Hope Cancer Care of Nevada-Pahrump
Pahrump, Nevada 89048
Pahrump, Nevada 89048
Renown Regional Medical Center
Reno, Nevada 89502
Reno, Nevada 89502
Saint Mary's Regional Medical Center
Reno, Nevada 89503
Reno, Nevada 89503
Radiation Oncology Associates
Reno, Nevada 89509
Reno, Nevada 89509
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire 03756
Lebanon, New Hampshire 03756
Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey 07920
Basking Ridge, New Jersey 07920
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
Memorial Sloan Kettering Monmouth
Middletown, New Jersey 07748
Middletown, New Jersey 07748
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
Memorial Sloan Kettering Bergen
Montvale, New Jersey 07645
Montvale, New Jersey 07645
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey 08903
New Brunswick, New Jersey 08903
Contact:
Site Public Contact
732-235-7356
Site Public Contact
732-235-7356
Holy Name Hospital
Teaneck, New Jersey 07666
Teaneck, New Jersey 07666
Contact:
Site Public Contact
201-833-6312
Site Public Contact
201-833-6312
Lovelace Medical Center-Saint Joseph Square
Albuquerque, New Mexico 87102
Albuquerque, New Mexico 87102
University of New Mexico Cancer Center
Albuquerque, New Mexico 87102
Albuquerque, New Mexico 87102
New Mexico Oncology Hematology Consultants
Albuquerque, New Mexico 87109
Albuquerque, New Mexico 87109
Presbyterian Kaseman Hospital
Albuquerque, New Mexico 87110
Albuquerque, New Mexico 87110
Memorial Medical Center - Las Cruces
Las Cruces, New Mexico 88011
Las Cruces, New Mexico 88011
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho, New Mexico 87124
Rio Rancho, New Mexico 87124
James J Peters VA Medical Center
Bronx, New York 10468
Bronx, New York 10468
Roswell Park Cancer Institute
Buffalo, New York 14263
Buffalo, New York 14263
Memorial Sloan Kettering Commack
Commack, New York 11725
Commack, New York 11725
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
Glens Falls Hospital
Glens Falls, New York 12801
Glens Falls, New York 12801
Contact:
Site Public Contact
518-926-6700
Site Public Contact
518-926-6700
Memorial Sloan Kettering Westchester
Harrison, New York 10604
Harrison, New York 10604
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York 10016
New York, New York 10016
Memorial Sloan Kettering Cancer Center
New York, New York 10065
New York, New York 10065
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
NYP/Weill Cornell Medical Center
New York, New York 10065
New York, New York 10065
Contact:
Site Public Contact
212-746-1848
Site Public Contact
212-746-1848
University of Rochester
Rochester, New York 14642
Rochester, New York 14642
Contact:
Site Public Contact
585-275-5830
Site Public Contact
585-275-5830
Memorial Sloan Kettering Nassau
Uniondale, New York 11553
Uniondale, New York 11553
Contact:
Site Public Contact
212-639-7592
Site Public Contact
212-639-7592
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina 28328
Clinton, North Carolina 28328
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina 27534
Goldsboro, North Carolina 27534
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina 28791
Hendersonville, North Carolina 28791
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina 28546
Jacksonville, North Carolina 28546
Vidant Oncology-Kenansville
Kenansville, North Carolina 28349
Kenansville, North Carolina 28349
Vidant Oncology-Kinston
Kinston, North Carolina 28501
Kinston, North Carolina 28501
Vidant Oncology-Richlands
Richlands, North Carolina 28574
Richlands, North Carolina 28574
Sanford Bismarck Medical Center
Bismarck, North Dakota 58501
Bismarck, North Dakota 58501
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota 58103
Fargo, North Dakota 58103
Sanford South University Medical Center
Fargo, North Dakota 58103
Fargo, North Dakota 58103
Contact:
Site Public Contact
701-234-6161
Site Public Contact
701-234-6161
Sanford Medical Center Fargo
Fargo, North Dakota 58104
Fargo, North Dakota 58104
Contact:
Site Public Contact
800-437-4010
Site Public Contact
800-437-4010
Sanford Broadway Medical Center
Fargo, North Dakota 58122
Fargo, North Dakota 58122
Sanford Roger Maris Cancer Center
Fargo, North Dakota 58122
Fargo, North Dakota 58122
Essentia Health - Jamestown Clinic
Jamestown, North Dakota 58401
Jamestown, North Dakota 58401
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio 44122
Beachwood, Ohio 44122
Indu and Raj Soin Medical Center
Beavercreek, Ohio 45431
Beavercreek, Ohio 45431
Strecker Cancer Center-Belpre
Belpre, Ohio 45714
Belpre, Ohio 45714
Saint Elizabeth Boardman Hospital
Boardman, Ohio 44512
Boardman, Ohio 44512
Hematology and Oncology Associates Inc
Canton, Ohio 44708
Canton, Ohio 44708
Mercy Medical Center
Canton, Ohio 44708
Canton, Ohio 44708
Contact:
Site Public Contact
888-293-4673
Site Public Contact
888-293-4673
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio 45459
Centerville, Ohio 45459
Miami Valley Hospital South
Centerville, Ohio 45459
Centerville, Ohio 45459
Geauga Hospital
Chardon, Ohio 44024
Chardon, Ohio 44024
Adena Regional Medical Center
Chillicothe, Ohio 45601
Chillicothe, Ohio 45601
University of Cincinnati/Barrett Cancer Center
Cincinnati, Ohio 45219
Cincinnati, Ohio 45219
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio 45220
Cincinnati, Ohio 45220
Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio 45236
Cincinnati, Ohio 45236
Bethesda North Hospital
Cincinnati, Ohio 45242
Cincinnati, Ohio 45242
TriHealth Cancer Institute-Westside
Cincinnati, Ohio 45247
Cincinnati, Ohio 45247
TriHealth Cancer Institute-Anderson
Cincinnati, Ohio 45255
Cincinnati, Ohio 45255
Case Western Reserve University
Cleveland, Ohio 44106
Cleveland, Ohio 44106
MetroHealth Medical Center
Cleveland, Ohio 44109
Cleveland, Ohio 44109
Mount Carmel East Hospital
Columbus, Ohio 43213
Columbus, Ohio 43213
Columbus Oncology and Hematology Associates Inc
Columbus, Ohio 43214
Columbus, Ohio 43214
Riverside Methodist Hospital
Columbus, Ohio 43214
Columbus, Ohio 43214
Grant Medical Center
Columbus, Ohio 43215
Columbus, Ohio 43215
The Mark H Zangmeister Center
Columbus, Ohio 43219
Columbus, Ohio 43219
Mount Carmel Health Center West
Columbus, Ohio 43222
Columbus, Ohio 43222
Doctors Hospital
Columbus, Ohio 43228
Columbus, Ohio 43228
Miami Valley Hospital
Dayton, Ohio 45409
Dayton, Ohio 45409
Dayton Physician LLC-Miami Valley Hospital North
Dayton, Ohio 45415
Dayton, Ohio 45415
Miami Valley Hospital North
Dayton, Ohio 45415
Dayton, Ohio 45415
Dayton Veterans Affairs Medical Center
Dayton, Ohio 45428
Dayton, Ohio 45428
Delaware Health Center-Grady Cancer Center
Delaware, Ohio 43015
Delaware, Ohio 43015
Grady Memorial Hospital
Delaware, Ohio 43015
Delaware, Ohio 43015
Dublin Methodist Hospital
Dublin, Ohio 43016
Dublin, Ohio 43016
Mercy Cancer Center-Elyria
Elyria, Ohio 44035
Elyria, Ohio 44035
Armes Family Cancer Center
Findlay, Ohio 45840
Findlay, Ohio 45840
Blanchard Valley Hospital
Findlay, Ohio 45840
Findlay, Ohio 45840
Orion Cancer Care
Findlay, Ohio 45840
Findlay, Ohio 45840
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio 45005-1066
Franklin, Ohio 45005-1066
Dayton Physicians LLC-Atrium
Franklin, Ohio 45005
Franklin, Ohio 45005
Central Ohio Breast and Endocrine Surgery
Gahanna, Ohio 43230
Gahanna, Ohio 43230
Dayton Physicians LLC-Wayne
Greenville, Ohio 45331
Greenville, Ohio 45331
Wayne Hospital
Greenville, Ohio 45331
Greenville, Ohio 45331
Mount Carmel Grove City Hospital
Grove City, Ohio 43123
Grove City, Ohio 43123
Greater Dayton Cancer Center
Kettering, Ohio 45409
Kettering, Ohio 45409
Kettering Medical Center
Kettering, Ohio 45429
Kettering, Ohio 45429
Fairfield Medical Center
Lancaster, Ohio 43130
Lancaster, Ohio 43130
OhioHealth Mansfield Hospital
Mansfield, Ohio 44903
Mansfield, Ohio 44903
Marietta Memorial Hospital
Marietta, Ohio 45750
Marietta, Ohio 45750
OhioHealth Marion General Hospital
Marion, Ohio 43302
Marion, Ohio 43302
UH Seidman Cancer Center at Landerbrook Health Center
Mayfield Heights, Ohio 44124
Mayfield Heights, Ohio 44124
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio 44060
Mentor, Ohio 44060
UH Seidman Cancer Center at Southwest General Hospital
Middleburg Heights, Ohio 44130
Middleburg Heights, Ohio 44130
Knox Community Hospital
Mount Vernon, Ohio 43050
Mount Vernon, Ohio 43050
Licking Memorial Hospital
Newark, Ohio 43055
Newark, Ohio 43055
Newark Radiation Oncology
Newark, Ohio 43055
Newark, Ohio 43055
University Hospitals Parma Medical Center
Parma, Ohio 44129
Parma, Ohio 44129
Southern Ohio Medical Center
Portsmouth, Ohio 45662
Portsmouth, Ohio 45662
University Hospitals Portage Medical Center
Ravenna, Ohio 44266
Ravenna, Ohio 44266
UH Seidman Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio 44870
Sandusky, Ohio 44870
Dayton Physicians LLC-Upper Valley
Troy, Ohio 45373
Troy, Ohio 45373
Upper Valley Medical Center
Troy, Ohio 45373
Troy, Ohio 45373
University Hospitals Sharon Health Center
Wadsworth, Ohio 44281
Wadsworth, Ohio 44281
Saint Joseph Warren Hospital
Warren, Ohio 44484
Warren, Ohio 44484
University Pointe
West Chester, Ohio 45069
West Chester, Ohio 45069
Saint Ann's Hospital
Westerville, Ohio 43081
Westerville, Ohio 43081
UH Seidman Cancer Center at Saint John Medical Center
Westlake, Ohio 44145
Westlake, Ohio 44145
UHHS-Westlake Medical Center
Westlake, Ohio 44145
Westlake, Ohio 44145
Saint Elizabeth Youngstown Hospital
Youngstown, Ohio 44501
Youngstown, Ohio 44501
Genesis Healthcare System Cancer Care Center
Zanesville, Ohio 43701
Zanesville, Ohio 43701
Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma 73505
Lawton, Oklahoma 73505
Contact:
Site Public Contact
877-231-4440
Site Public Contact
877-231-4440
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma 73104
Oklahoma City, Oklahoma 73104
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma 73120
Oklahoma City, Oklahoma 73120
Contact:
Site Public Contact
405-752-3402
Site Public Contact
405-752-3402
Cancer Treatment Centers of America
Tulsa, Oklahoma 74133
Tulsa, Oklahoma 74133
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma 74146
Tulsa, Oklahoma 74146
Contact:
Site Public Contact
918-505-3200
Site Public Contact
918-505-3200
Saint Alphonsus Medical Center-Baker City
Baker City, Oregon 97814
Baker City, Oregon 97814
Saint Charles Health System
Bend, Oregon 97701
Bend, Oregon 97701
Clackamas Radiation Oncology Center
Clackamas, Oregon 97015
Clackamas, Oregon 97015
Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon 97015
Clackamas, Oregon 97015
Bay Area Hospital
Coos Bay, Oregon 97420
Coos Bay, Oregon 97420
Good Samaritan Hospital
Corvallis, Oregon 97330
Corvallis, Oregon 97330
Legacy Mount Hood Medical Center
Gresham, Oregon 97030
Gresham, Oregon 97030
Contact:
Site Public Contact
503-413-2150
Site Public Contact
503-413-2150
Providence Newberg Medical Center
Newberg, Oregon 97132
Newberg, Oregon 97132
Saint Alphonsus Medical Center-Ontario
Ontario, Oregon 97914
Ontario, Oregon 97914
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon 97210
Portland, Oregon 97210
Providence Portland Medical Center
Portland, Oregon 97213
Portland, Oregon 97213
Providence Saint Vincent Medical Center
Portland, Oregon 97225
Portland, Oregon 97225
Oregon Health and Science University
Portland, Oregon 97239
Portland, Oregon 97239
Saint Charles Health System-Redmond
Redmond, Oregon 97756
Redmond, Oregon 97756
Contact:
Site Public Contact
541-706-2909
Site Public Contact
541-706-2909
Legacy Meridian Park Hospital
Tualatin, Oregon 97062
Tualatin, Oregon 97062
Contact:
Site Public Contact
503-413-1742
Site Public Contact
503-413-1742
Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania 19317
Chadds Ford, Pennsylvania 19317
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania 19107
Philadelphia, Pennsylvania 19107
Contact:
Site Public Contact
215-955-6084
Site Public Contact
215-955-6084
Eastern Regional Medical Center
Philadelphia, Pennsylvania 19124
Philadelphia, Pennsylvania 19124
AnMed Health Cancer Center
Anderson, South Carolina 29621
Anderson, South Carolina 29621
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina 29316
Boiling Springs, South Carolina 29316
Prisma Health Cancer Institute - Easley
Easley, South Carolina 29640
Easley, South Carolina 29640
Gibbs Cancer Center-Gaffney
Gaffney, South Carolina 29341
Gaffney, South Carolina 29341
Saint Francis Hospital
Greenville, South Carolina 29601
Greenville, South Carolina 29601
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina 29605
Greenville, South Carolina 29605
Prisma Health Cancer Institute - Faris
Greenville, South Carolina 29605
Greenville, South Carolina 29605
Prisma Health Greenville Memorial Hospital
Greenville, South Carolina 29605
Greenville, South Carolina 29605
Saint Francis Cancer Center
Greenville, South Carolina 29607
Greenville, South Carolina 29607
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina 29615
Greenville, South Carolina 29615
Prisma Health Cancer Institute - Greer
Greer, South Carolina 29650
Greer, South Carolina 29650
Gibbs Cancer Center-Pelham
Greer, South Carolina 29651
Greer, South Carolina 29651
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina 29672
Seneca, South Carolina 29672
Spartanburg Medical Center
Spartanburg, South Carolina 29303
Spartanburg, South Carolina 29303
MGC Hematology Oncology-Union
Union, South Carolina 29379
Union, South Carolina 29379
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota 57104
Sioux Falls, South Dakota 57104
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota 57117-5134
Sioux Falls, South Dakota 57117-5134
Wellmont Bristol Regional Medical Center
Bristol, Tennessee 37620
Bristol, Tennessee 37620
Baptist Memorial Hospital and Cancer Center-Collierville
Collierville, Tennessee 38017
Collierville, Tennessee 38017
Cookeville Regional Medical Center
Cookeville, Tennessee 38501
Cookeville, Tennessee 38501
Contact:
Site Public Contact
931-783-2714
Site Public Contact
931-783-2714
Vanderbilt-Ingram Cancer Center at Franklin
Franklin, Tennessee 37067
Franklin, Tennessee 37067
Contact:
Site Public Contact
800-811-8480
Site Public Contact
800-811-8480
Vanderbilt-Ingram Cancer Center Cool Springs
Franklin, Tennessee 37067
Franklin, Tennessee 37067
Contact:
Site Public Contact
800-811-8480
Site Public Contact
800-811-8480
The West Clinic - Wolf River
Germantown, Tennessee 38138
Germantown, Tennessee 38138
Regional Cancer Center at Indian Path Community Hospital
Kingsport, Tennessee 37660
Kingsport, Tennessee 37660
Wellmont Holston Valley Hospital and Medical Center
Kingsport, Tennessee 37660
Kingsport, Tennessee 37660
The West Clinic - Mid-Town
Memphis, Tennessee 38104
Memphis, Tennessee 38104
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee 38120
Memphis, Tennessee 38120
Vanderbilt Breast Center at One Hundred Oaks
Nashville, Tennessee 37204
Nashville, Tennessee 37204
Contact:
Site Public Contact
800-811-8480
Site Public Contact
800-811-8480
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee 37232
Nashville, Tennessee 37232
Contact:
Site Public Contact
800-811-8480
Site Public Contact
800-811-8480
Hendrick Medical Center
Abilene, Texas 79601
Abilene, Texas 79601
Contact:
Site Public Contact
325-670-6340
Site Public Contact
325-670-6340
Saint Joseph Regional Cancer Center
Bryan, Texas 77802
Bryan, Texas 77802
Parkland Memorial Hospital
Dallas, Texas 75235
Dallas, Texas 75235
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas 75390
Dallas, Texas 75390
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, Texas 76104
Fort Worth, Texas 76104
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas 77030
Houston, Texas 77030
Ben Taub General Hospital
Houston, Texas 77030
Houston, Texas 77030
Contact:
Site Public Contact
713-873-2000
Site Public Contact
713-873-2000
M D Anderson Cancer Center
Houston, Texas 77030
Houston, Texas 77030
Michael E DeBakey VA Medical Center
Houston, Texas 77030
Houston, Texas 77030
Contact:
Site Public Contact
800-553-2278
Site Public Contact
800-553-2278
UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas 75080
Richardson, Texas 75080
University of Texas Health Science Center at San Antonio
San Antonio, Texas 78229
San Antonio, Texas 78229
Farmington Health Center
Farmington, Utah 84025
Farmington, Utah 84025
University of Utah Sugarhouse Health Center
Salt Lake City, Utah 84106
Salt Lake City, Utah 84106
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah 84112
Salt Lake City, Utah 84112
Central Vermont Medical Center/National Life Cancer Treatment
Berlin, Vermont 05602
Berlin, Vermont 05602
Contact:
Site Public Contact
802-225-5400
Site Public Contact
802-225-5400
University of Vermont Medical Center
Burlington, Vermont 05401
Burlington, Vermont 05401
University of Vermont and State Agricultural College
Burlington, Vermont 05405
Burlington, Vermont 05405
Wellmont Medical Associates-Bristol
Bristol, Virginia 24201
Bristol, Virginia 24201
Southwest VA Regional Cancer Center
Norton, Virginia 24273
Norton, Virginia 24273
VCU Massey Cancer Center at Stony Point
Richmond, Virginia 23235
Richmond, Virginia 23235
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia 23298
Richmond, Virginia 23298
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington 98520
Aberdeen, Washington 98520
Overlake Medical Center
Bellevue, Washington 98004
Bellevue, Washington 98004
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington 98225
Bellingham, Washington 98225
Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington 98310
Bremerton, Washington 98310
Harrison Medical Center
Bremerton, Washington 98310
Bremerton, Washington 98310
Highline Medical Center-Main Campus
Burien, Washington 98166
Burien, Washington 98166
Providence Regional Cancer System-Centralia
Centralia, Washington 98531
Centralia, Washington 98531
Swedish Cancer Institute-Edmonds
Edmonds, Washington 98026
Edmonds, Washington 98026
Saint Elizabeth Hospital
Enumclaw, Washington 98022
Enumclaw, Washington 98022
Providence Regional Cancer Partnership
Everett, Washington 98201
Everett, Washington 98201
Saint Francis Hospital
Federal Way, Washington 98003
Federal Way, Washington 98003
Swedish Cancer Institute-Issaquah
Issaquah, Washington 98029
Issaquah, Washington 98029
Kadlec Clinic Hematology and Oncology
Kennewick, Washington 99336
Kennewick, Washington 99336
Providence Regional Cancer System-Lacey
Lacey, Washington 98503
Lacey, Washington 98503
Saint Clare Hospital
Lakewood, Washington 98499
Lakewood, Washington 98499
PeaceHealth Saint John Medical Center
Longview, Washington 98632
Longview, Washington 98632
Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, Washington 98370
Poulsbo, Washington 98370
Valley Medical Center
Renton, Washington 98055
Renton, Washington 98055
Pacific Gynecology Specialists
Seattle, Washington 98104
Seattle, Washington 98104
Swedish Medical Center-Ballard Campus
Seattle, Washington 98107
Seattle, Washington 98107
Swedish Medical Center-First Hill
Seattle, Washington 98122-4307
Seattle, Washington 98122-4307
Swedish Medical Center-Cherry Hill
Seattle, Washington 98122-5711
Seattle, Washington 98122-5711
PeaceHealth United General Medical Center
Sedro-Woolley, Washington 98284
Sedro-Woolley, Washington 98284
Providence Regional Cancer System-Shelton
Shelton, Washington 98584
Shelton, Washington 98584
Franciscan Research Center-Northwest Medical Plaza
Tacoma, Washington 98405
Tacoma, Washington 98405
PeaceHealth Southwest Medical Center
Vancouver, Washington 98664
Vancouver, Washington 98664
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington 98684
Vancouver, Washington 98684
Legacy Salmon Creek Hospital
Vancouver, Washington 98686
Vancouver, Washington 98686
Contact:
Site Public Contact
503-413-2150
Site Public Contact
503-413-2150
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington 99362
Walla Walla, Washington 99362
Providence Regional Cancer System-Yelm
Yelm, Washington 98597
Yelm, Washington 98597
United Hospital Center
Bridgeport, West Virginia 26330
Bridgeport, West Virginia 26330
WVUH-Berkely Medical Center
Martinsburg, West Virginia 25401
Martinsburg, West Virginia 25401
West Virginia University Healthcare
Morgantown, West Virginia 26506
Morgantown, West Virginia 26506
Camden Clark Medical Center
Parkersburg, West Virginia 26101
Parkersburg, West Virginia 26101
Duluth Clinic Ashland
Ashland, Wisconsin 54806
Ashland, Wisconsin 54806
Northwest Wisconsin Cancer Center
Ashland, Wisconsin 54806
Ashland, Wisconsin 54806
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin 53105
Burlington, Wisconsin 53105
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin 54729
Chippewa Falls, Wisconsin 54729
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin 54701
Eau Claire, Wisconsin 54701
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin 54701
Eau Claire, Wisconsin 54701
Contact:
Site Public Contact
855-776-0015
Site Public Contact
855-776-0015
Aurora Health Center-Fond du Lac
Fond Du Lac, Wisconsin 54937
Fond Du Lac, Wisconsin 54937
Aurora Health Care Germantown Health Center
Germantown, Wisconsin 53022
Germantown, Wisconsin 53022
Aurora Cancer Care-Grafton
Grafton, Wisconsin 53024
Grafton, Wisconsin 53024
Bellin Memorial Hospital
Green Bay, Wisconsin 54301
Green Bay, Wisconsin 54301
Contact:
Site Public Contact
920-435-8326
Site Public Contact
920-435-8326
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin 54301
Green Bay, Wisconsin 54301
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin 54303
Green Bay, Wisconsin 54303
Aurora BayCare Medical Center
Green Bay, Wisconsin 54311
Green Bay, Wisconsin 54311
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin 53142
Kenosha, Wisconsin 53142
Gundersen Lutheran Medical Center
La Crosse, Wisconsin 54601
La Crosse, Wisconsin 54601
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin 54601
La Crosse, Wisconsin 54601
Contact:
Site Public Contact
855-776-0015
Site Public Contact
855-776-0015
Marshfield Clinic - Ladysmith Center
Ladysmith, Wisconsin 54848
Ladysmith, Wisconsin 54848
University of Wisconsin Hospital and Clinics
Madison, Wisconsin 53792
Madison, Wisconsin 53792
Contact:
Site Public Contact
800-622-8922
Site Public Contact
800-622-8922
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin 54143
Marinette, Wisconsin 54143
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin 54449
Marshfield, Wisconsin 54449
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin 53209
Milwaukee, Wisconsin 53209
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin 53215
Milwaukee, Wisconsin 53215
Aurora Sinai Medical Center
Milwaukee, Wisconsin 53233
Milwaukee, Wisconsin 53233
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin 54548
Minocqua, Wisconsin 54548
ProHealth D N Greenwald Center
Mukwonago, Wisconsin 53149
Mukwonago, Wisconsin 53149
Cancer Center of Western Wisconsin
New Richmond, Wisconsin 54017
New Richmond, Wisconsin 54017
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin 53066
Oconomowoc, Wisconsin 53066
Contact:
Site Public Contact
262-928-7878
Site Public Contact
262-928-7878
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin 54154
Oconto Falls, Wisconsin 54154
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin 54904
Oshkosh, Wisconsin 54904
Aurora Cancer Care-Racine
Racine, Wisconsin 53406
Racine, Wisconsin 53406
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin 54868
Rice Lake, Wisconsin 54868
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin 53081
Sheboygan, Wisconsin 53081
Marshfield Clinic Stevens Point Center
Stevens Point, Wisconsin 54482
Stevens Point, Wisconsin 54482
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin 54235-1495
Sturgeon Bay, Wisconsin 54235-1495
Aurora Medical Center in Summit
Summit, Wisconsin 53066
Summit, Wisconsin 53066
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin 54241
Two Rivers, Wisconsin 54241
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin 53188
Waukesha, Wisconsin 53188
Contact:
Site Public Contact
262-928-7632
Site Public Contact
262-928-7632
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin 53188
Waukesha, Wisconsin 53188
Marshfield Clinic-Wausau Center
Wausau, Wisconsin 54401
Wausau, Wisconsin 54401
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin 53226
Wauwatosa, Wisconsin 53226
Aurora West Allis Medical Center
West Allis, Wisconsin 53227
West Allis, Wisconsin 53227
Marshfield Clinic - Weston Center
Weston, Wisconsin 54476
Weston, Wisconsin 54476
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin 54494
Wisconsin Rapids, Wisconsin 54494
Billings Clinic-Cody
Cody, Wyoming 82414
Cody, Wyoming 82414
Welch Cancer Center
Sheridan, Wyoming 82801
Sheridan, Wyoming 82801
More Details
- NCT ID
- NCT03768414
- Status
- Recruiting
- Sponsor
- Southwest Oncology Group
Detailed Description
PRIMARY OBJECTIVES: I. To compare overall survival (OS) in patients with untreated, advanced biliary cancers treated with gemcitabine hydrochloride (gemcitabine) and cisplatin (GC) versus those treated with gemcitabine, cisplatin, and nab-Paclitaxel (GCN). SECONDARY OBJECTIVES: I. To compare progression-free survival (PFS) in patients treated with GC versus GCN. II. To compare overall response rate (ORR), complete and partial, confirmed and unconfirmed, in the subset of patients with measurable disease treated with GC versus GCN. III. To compare disease control rate (confirmed and unconfirmed; complete response + partial response + stable disease) (DCR) in patients treated with GC versus GCN. IV. To evaluate the frequency and severity of toxicity associated with GC and GCN in the patient population. V. To explore the correlation between change in cancer antigen 19-9 (CA19-9) levels from baseline to post-treatment (after 3 cycles) and overall response rate, in each treatment arm separately and in the total cohort. ADDITIONAL OBJECTIVES: I. To bank tissue and blood for future translational medicine studies. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients receive nab-paclitaxel intravenously (IV) over 30 minutes, cisplatin IV over 60 minutes, and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM II: Patients receive cisplatin IV over 60 minutes and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 6 months for 2 years and then at the end of year 3.