Purpose

The primary purpose of the Research Database is to have a comprehensive source of observational data that can be used to study HSC transplantation and cellular therapies. A secondary purpose of the Research Database is to have a comprehensive source of data to study marrow toxic injuries. Objectives: To learn more about what makes stem cell transplants and cellular therapies work well such as: - Determine how well recipients recover from their transplants or cellular therapy; - Determine how recovery after a transplant or cellular therapy can be improved; - Determine how a donor's or recipient's genetics impact recipient recovery after a transplant or cellular therapy; - Determine how access to transplant or cellular therapy for different groups of patients can be improved; - Determine how well donors recover from the collection procedures.

Conditions

Eligibility

Eligible Ages
All ages
Eligible Genders
All
Accepts Healthy Volunteers
No

Criteria


Eligibility to Participate in the Research Database

Recipient Eligibility Criteria:

- Any recipient of an unrelated or related donor or autologous HSC transplant in a
CIBMTR center is eligible to participate in the Research Database. This includes
adults with and without decision making capacity, and children.

Individual with Marrow Toxic Injury Eligibility Criteria:

- Any individual who is treated for a marrow toxic injury at a center participating in
the NMDP's Radiation Injury Transplant Network (RITN) is eligible to participate in
the Research Database. This includes adults with and without decision making capacity,
and children. Eligible individuals may have received supportive care only, growth
factor support, HSC transplant or other appropriate medical treatment for marrow toxic
injury. Treatments applied are at the discretion of the care facility, and are not
determined by the NMDP or CIBMTR.

Unrelated Donor Eligibility Criteria:

- All donors registered on the NMDP Registry who have been requested to donate a product
for a recipient are eligible to participate in the Research Database.

- All maternal cord blood donors are enrolled in the NMDP Cord Blood Bank
Investigational New Drug (IND) protocol, and sign an informed consent document
specific to that protocol. Data collected as part of the Cord Blood Bank protocol are
included in the Research Database.

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Recruiting Locations

Center for International Blood and Marrow Transplant Research
Minneapolis, Minnesota 55413

More Details

NCT ID
NCT01166009
Status
Recruiting
Sponsor
Center for International Blood and Marrow Transplant Research

Study Contact

Kay Gardner
763 406 3439
kgardner@nmdp.org

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.