Purpose

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery and have fewer side effects.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Criteria


- Histologically confirmed invasive carcinoma of the breast of any of the following
histologies (ductal, lobular, mammary, medullary, or tubular); in-situ disease alone
is not allowed

- Final American Joint Committee on Cancer (AJCC) stage IIa - IIIa (pathologic stage
T0N1a-2a, T1N1a-2a, T2N1a-2a, T3N0-2a, all M0 status); pathological stage for all
patients not receiving neoadjuvant chemotherapy; higher of the clinical or
pathological T and N stage, if receiving neoadjuvant chemotherapy; patients with
pathological N0 at the time of mastectomy are only eligible if biopsy-proven
clinically N1 or N2 disease is documented prior to induction chemotherapy

- No prior radiation therapy to the chest, neck or axilla

- No prior history of ipsilateral breast cancer (invasive disease or ductal breast
carcinoma in situ [DCIS]); lobular carcinoma in situ (LCIS) and benign breast disease
is allowed

- No history of prior or concurrent contralateral invasive breast cancer; benign breast
disease, LCIS or DCIS of contralateral breast is allowed

- No active collagen vascular diseases, such as: systemic lupus erythematous,
scleroderma, or dermatomyositis

- Negative inked histologic margins from mastectomy pathology (no invasive cells at
margin)

- No significant post mastectomy complications requiring an unplanned re-operation or
admission for intravenous (IV) antibiotics; re-operation for margins evaluation, nodal
completion and routine reconstruction is acceptable

- Radiation oncologist intends to treat all target volumes and respect all normal
tissues in accordance with the dosimetric constraints described (simulation before
registration recommended)

- Radiation oncologist is planning to treat regional lymph nodes including internal
mammary nodes and meet acceptable protocol dosimetric requirements

- Radiation oncologist is NOT planning to utilize a chest wall/scar boost

- Patient must have undergone immediate reconstruction at the time of mastectomy or be
planning to undergo reconstruction within 8 months after radiation

- For patients with diabetes, hemoglobin A1C test must have been performed =< 90 days
prior to registration

- No co-existing medical conditions with life expectancy < 5 years

- No other malignancy within 5 years of registration with the exception of basal cell or
squamous cell carcinoma of the skin treated with local resection only or carcinoma in
situ of the cervix

- Negative serum or urine beta-human chorionic gonadotropin (HCG) in women of
child-bearing potential =< 7 days prior to registration; a female of childbearing
potential is a sexually mature female who has not undergone a hysterectomy or
bilateral oophorectomy and has not been naturally postmenopausal for at least 12
consecutive months

- Women of child-bearing potential must agree to utilize a form of birth control or
agree to undergo sexual abstinence during radiation therapy

- Eastern Cooperative Oncology Group (ECOG) (Zubrod) performance status 0-1

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Supportive Care
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Group I (radiation therapy)
Patients undergo radiation therapy daily on Monday-Friday for 5-6 weeks.
  • Radiation: Radiation Therapy
    Undergo RT
  • Other: Questionnaire Administration
    Ancillary studies
  • Other: Quality-of-Life Assessment
    Ancillary studies
  • Other: Laboratory Biomarker Analysis
    Correlative studies
Experimental
Group II (hypofractionated radiation therapy)
Patients undergo hypofractionated radiation therapy daily on Monday-Friday for 3-4 weeks.
  • Other: Questionnaire Administration
    Ancillary studies
  • Other: Quality-of-Life Assessment
    Ancillary studies
  • Other: Laboratory Biomarker Analysis
    Correlative studies
  • Radiation: Hypofractionated Radiation Therapy
    Undergo hypofractionated RT

Recruiting Locations

Anchorage Associates in Radiation Medicine
Anchorage, Alaska 98508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Anchorage Radiation Therapy Center
Anchorage, Alaska 99504
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Breast Care and Surgery LLC
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Oncology and Hematology LLC
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Women's Cancer Care
Anchorage, Alaska 99508
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Anchorage Oncology Centre
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Katmai Oncology Group
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Providence Alaska Medical Center
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

CHI Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas 71913
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

University of Arkansas for Medical Sciences
Little Rock, Arkansas 72205
Contact:
Site Public Contact
501-686-8274

Kaiser Permanente-Deer Valley Medical Center
Antioch, California 94531
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California 91505
Contact:
Site Public Contact
818-847-4793
Madonna.Johnson@providence.org

City of Hope Corona
Corona, California 92879
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

UC Irvine Health Cancer Center-Newport
Costa Mesa, California 92627
Contact:
Site Public Contact
877-827-8839

City of Hope Comprehensive Cancer Center
Duarte, California 91010
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

Epic Care-Dublin
Dublin, California 94568
Contact:
Site Public Contact
925-875-1677

Bay Area Breast Surgeons Inc
Emeryville, California 94608
Contact:
Site Public Contact
510-835-9900

Epic Care Partners in Cancer Care
Emeryville, California 94608
Contact:
Site Public Contact
510-629-6682

Kaiser Permanente-Fremont
Fremont, California 94538
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Fresno Cancer Center
Fresno, California 93720
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Fresno
Fresno, California 93720
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Los Angeles County-USC Medical Center
Los Angeles, California 90033
Contact:
Site Public Contact
323-865-0451

USC / Norris Comprehensive Cancer Center
Los Angeles, California 90033
Contact:
Site Public Contact
323-865-0451

Cedars Sinai Medical Center
Los Angeles, California 90048
Contact:
Site Public Contact
310-423-8965

Contra Costa Regional Medical Center
Martinez, California 94553-3156
Contact:
Site Public Contact
925-957-5400

Kaiser Permanente-Modesto
Modesto, California 95356
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California 92663
Contact:
Site Public Contact
323-865-0451

Alta Bates Summit Medical Center - Summit Campus
Oakland, California 94609
Contact:
Site Public Contact
510-204-1414

Bay Area Tumor Institute
Oakland, California 94609
Contact:
Site Public Contact
510-465-2242
lradke@bati.org

Kaiser Permanente Oakland-Broadway
Oakland, California 94611
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Oakland
Oakland, California 94611
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California 92868
Contact:
Site Public Contact
877-827-8839
ucstudy@uci.edu

Keck Medical Center of USC Pasadena
Pasadena, California 91105
Contact:
Site Public Contact
323-865-0451

Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cordova, California 95670
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Redwood City
Redwood City, California 94063
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Richmond
Richmond, California 94801
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Rohnert Park Cancer Center
Rohnert Park, California 94928
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Roseville
Roseville, California 95661
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

The Permanente Medical Group-Roseville Radiation Oncology
Roseville, California 95678
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Downtown Commons
Sacramento, California 95814
Contact:
Site Public Contact
877-642-4691
kpoct@kp.org

Kaiser Permanente-South Sacramento
Sacramento, California 95823
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

South Sacramento Cancer Center
Sacramento, California 95823
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente - Sacramento
Sacramento, California 95825
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-San Francisco
San Francisco, California 94115
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Santa Teresa-San Jose
San Jose, California 95119
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente San Leandro
San Leandro, California 94577
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-San Rafael
San Rafael, California 94903
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser San Rafael-Gallinas
San Rafael, California 94903
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California 95051
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Santa Rosa
Santa Rosa, California 95403
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

City of Hope South Pasadena
South Pasadena, California 91030
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

Kaiser Permanente Cancer Treatment Center
South San Francisco, California 94080
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-South San Francisco
South San Francisco, California 94080
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Stockton
Stockton, California 95210
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente Medical Center-Vacaville
Vacaville, California 95688
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Vallejo
Vallejo, California 94589
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Kaiser Permanente-Walnut Creek
Walnut Creek, California 94596
Contact:
Site Public Contact
877-642-4691
Kpoct@kp.org

Epic Care Cyberknife Center
Walnut Creek, California 94597
Contact:
Site Public Contact
510-465-8016
somega@bati.org

Rocky Mountain Cancer Centers-Aurora
Aurora, Colorado 80012
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

University of Colorado Hospital
Aurora, Colorado 80045
Contact:
Site Public Contact
720-848-0650

Rocky Mountain Cancer Centers-Boulder
Boulder, Colorado 80304
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Penrose-Saint Francis Healthcare
Colorado Springs, Colorado 80907
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado 80907
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

UCHealth Memorial Hospital Central
Colorado Springs, Colorado 80909
Contact:
Site Public Contact
719-365-2406

Denver Health Medical Center
Denver, Colorado 80204
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

National Jewish Health-Main Campus
Denver, Colorado 80206
Contact:
Site Public Contact
877-225-5654
glicht@co-cancerresearch.org

The Women's Imaging Center
Denver, Colorado 80209
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Porter Adventist Hospital
Denver, Colorado 80210
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Colorado Blood Cancer Institute
Denver, Colorado 80218
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Presbyterian - Saint Lukes Medical Center - Health One
Denver, Colorado 80218
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Rocky Mountain Cancer Centers-Midtown
Denver, Colorado 80218
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

SCL Health Saint Joseph Hospital
Denver, Colorado 80218
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Rocky Mountain Cancer Centers-Rose
Denver, Colorado 80220
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Western Surgical Care
Denver, Colorado 80220
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Mercy Medical Center
Durango, Colorado 81301
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Southwest Oncology PC
Durango, Colorado 81301
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Comprehensive Cancer Care and Research Institute of Colorado LLC
Englewood, Colorado 80113
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Swedish Medical Center
Englewood, Colorado 80113
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Valley View Hospital Cancer Center
Glenwood Springs, Colorado 81601
Contact:
Site Public Contact
970-384-7570

Mountain Blue Cancer Care Center
Golden, Colorado 80401
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

National Jewish Health-Western Hematology Oncology
Golden, Colorado 80401
Contact:
Site Public Contact
303-777-2663
glicht@co-cancerresearch.org

Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado 81501
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

North Colorado Medical Center
Greeley, Colorado 80631
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Good Samaritan Medical Center
Lafayette, Colorado 80026
Contact:
Site Public Contact
303-673-1622

Rocky Mountain Cancer Centers-Lakewood
Lakewood, Colorado 80228
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Anthony Hospital
Lakewood, Colorado 80228
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Littleton
Littleton, Colorado 80120
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Littleton Adventist Hospital
Littleton, Colorado 80122
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Sky Ridge
Lone Tree, Colorado 80124
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Longmont United Hospital
Longmont, Colorado 80501
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado 80501
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

McKee Medical Center
Loveland, Colorado 80539
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Parker Adventist Hospital
Parker, Colorado 80138
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Parker
Parker, Colorado 80138
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Mary Corwin Medical Center
Pueblo, Colorado 81004
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers - Pueblo
Pueblo, Colorado 81008
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

National Jewish Health-Northern Hematology Oncology
Thornton, Colorado 80260
Contact:
Site Public Contact
303-777-2663
glicht@co-cancerresearch.org

Rocky Mountain Cancer Centers-Thornton
Thornton, Colorado 80260
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

SCL Health Lutheran Medical Center
Wheat Ridge, Colorado 80033
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Middlesex Hospital
Middletown, Connecticut 06457
Contact:
Site Public Contact
860-358-2058
beth_slifer@midhosp.org

Beebe Medical Center
Lewes, Delaware 19958
Contact:
Site Public Contact
302-645-3770
Dmiskin@Beebehealthcare.org

Delaware Clinical and Laboratory Physicians PA
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Helen F Graham Cancer Center
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Medical Oncology Hematology Consultants PA
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Regional Hematology and Oncology PA
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Christiana Care Health System-Christiana Hospital
Newark, Delaware 19718
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Beebe Health Campus
Rehoboth Beach, Delaware 19971
Contact:
Site Public Contact
302-645-3100
Dmiskin@Beebehealthcare.org

Nanticoke Memorial Hospital
Seaford, Delaware 19973
Contact:
Site Public Contact
302-645-3100
Dmiskin@Beebehealthcare.org

Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware 19801
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Florida Hospital Cancer Institute Altamonte
Altamonte Springs, Florida 32701
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

John Fitzgerald Kennedy Medical Center
Atlantis, Florida 33462
Contact:
Site Public Contact
561-964-2662

University of Florida Health Science Center - Gainesville
Gainesville, Florida 32610
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida 33021
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Mayo Clinic in Florida
Jacksonville, Florida 32224-9980
Contact:
Site Public Contact
855-776-0015

Florida Hospital Kissimmee
Kissimmee, Florida 34744
Contact:
Site Public Contact
407-303-5999

Florida Hospital Orlando
Orlando, Florida 32803
Contact:
Site Public Contact
407-303-2090
FH.Cancer.Research@flhosp.org

Florida Urology Associates-Orlando
Orlando, Florida 32803
Contact:
Site Public Contact
407-897-3499

Florida Hospital East Orlando
Orlando, Florida 32822
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Memorial Hospital West
Pembroke Pines, Florida 33028
Contact:
Site Public Contact
954-265-4325

Moffitt Cancer Center
Tampa, Florida 33612
Contact:
Site Public Contact
800-456-7121
canceranswers@moffitt.org

Florida Hospital Cancer Institute Winter Park
Winter Park, Florida 32792
Contact:
Site Public Contact
407-646-7777

Grady Health System
Atlanta, Georgia 30303
Contact:
Site Public Contact
404-489-9164

Emory University Hospital Midtown
Atlanta, Georgia 30308
Contact:
Site Public Contact
888-946-7447

Piedmont Hospital
Atlanta, Georgia 30309
Contact:
Site Public Contact
404-425-7943
ORS@piedmont.org

Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia 30322
Contact:
Site Public Contact
404-778-1868

Emory Saint Joseph's Hospital
Atlanta, Georgia 30342
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia 31405
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Summit Cancer Care-Candler
Savannah, Georgia 31405
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii 96819
Contact:
Site Public Contact
808-432-5195
shelley.a.clark@kp.org

Saint Luke's Mountain States Tumor Institute
Boise, Idaho 83712
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Kootenai Medical Center
Coeur d'Alene, Idaho 83814
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Luke's Mountain States Tumor Institute - Fruitland
Fruitland, Idaho 83619
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Saint Luke's Mountain States Tumor Institute - Meridian
Meridian, Idaho 83642
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Saint Luke's Mountain States Tumor Institute - Nampa
Nampa, Idaho 83686
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Kootenai Cancer Center
Post Falls, Idaho 83854
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Kootenai Cancer Clinic
Sandpoint, Idaho 83864
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Luke's Mountain States Tumor Institute-Twin Falls
Twin Falls, Idaho 83301
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Rush - Copley Medical Center
Aurora, Illinois 60504
Contact:
Site Public Contact
630-978-6212
Cancer.Research@rushcopley.com

Illinois CancerCare-Bloomington
Bloomington, Illinois 61704
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Loyola Center for Health at Burr Ridge
Burr Ridge, Illinois 60527
Contact:
Site Public Contact
708-216-9000

Illinois CancerCare-Canton
Canton, Illinois 61520
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Memorial Hospital of Carbondale
Carbondale, Illinois 62902
Contact:
Site Public Contact
618-457-5200
clinical.research@sih.net

SIH Cancer Institute
Carterville, Illinois 62918
Contact:
Site Public Contact
618-985-3333
clinical.research@sih.net

Illinois CancerCare-Carthage
Carthage, Illinois 62321
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Centralia Oncology Clinic
Centralia, Illinois 62801
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Northwestern University
Chicago, Illinois 60611
Contact:
Site Public Contact
312-695-1301
cancer@northwestern.edu

Rush University Medical Center
Chicago, Illinois 60612
Contact:
Site Public Contact
312-942-5498
clinical_trials@rush.edu

University of Chicago Comprehensive Cancer Center
Chicago, Illinois 60637
Contact:
Site Public Contact
773-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Carle on Vermilion
Danville, Illinois 61832
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois 62526
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Decatur Memorial Hospital
Decatur, Illinois 62526
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Carle Physician Group-Effingham
Effingham, Illinois 62401
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Crossroads Cancer Center
Effingham, Illinois 62401
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Illinois CancerCare-Eureka
Eureka, Illinois 61530
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Galesburg
Galesburg, Illinois 61401
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Western Illinois Cancer Treatment Center
Galesburg, Illinois 61401
Contact:
Site Public Contact
309-344-2831

AMITA Health Cancer Institute and Outpatient Center
Hinsdale, Illinois 60521
Contact:
Site Public Contact
630-286-5500

Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois 61443
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois 60045
Contact:
Site Public Contact
cancertrials@northwestern.edu

Condell Memorial Hospital
Libertyville, Illinois 60048
Contact:
Site Public Contact
630-929-6129
advocateresearch@advocatehealth.com

Illinois CancerCare-Macomb
Macomb, Illinois 61455
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois 61938
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Loyola University Medical Center
Maywood, Illinois 60153
Contact:
Site Public Contact
708-226-4357

Marjorie Weinberg Cancer Center at Loyola-Gottlieb
Melrose Park, Illinois 60160
Contact:
Site Public Contact
708-450-4554

UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois 60451
Contact:
Site Public Contact
773-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Loyola Center for Cancer Care and Research
Orland Park, Illinois 60462
Contact:
Site Public Contact
708-216-9000

University of Chicago Medicine-Orland Park
Orland Park, Illinois 60462
Contact:
Site Public Contact
773-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois 61350
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Pekin
Pekin, Illinois 61554
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Pekin, Illinois 61554
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peoria
Peoria, Illinois 61615
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois 61615
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Peoria, Illinois 61636
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

OSF Saint Francis Medical Center
Peoria, Illinois 61637
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peru
Peru, Illinois 61354
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Valley Radiation Oncology
Peru, Illinois 61354
Contact:
Site Public Contact
815-664-4141

Illinois CancerCare-Princeton
Princeton, Illinois 61356
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

SwedishAmerican Regional Cancer Center/ACT
Rockford, Illinois 61114
Contact:
Site Public Contact
779-696-9400
cancercare@swedishamerican.org

Southern Illinois University School of Medicine
Springfield, Illinois 62702
Contact:
Site Public Contact
217-545-7929

Springfield Clinic
Springfield, Illinois 62702
Contact:
Site Public Contact
800-444-7541

Memorial Medical Center
Springfield, Illinois 62781
Contact:
Site Public Contact
217-788-3528

Cancer Care Specialists of Illinois-Swansea
Swansea, Illinois 62226
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Southwest Illinois Health Services LLP
Swansea, Illinois 62226
Contact:
Site Public Contact
618-236-1000
lynns@thecancercenter.com

Carle Cancer Center
Urbana, Illinois 61801
Contact:
Site Public Contact
800-446-5532
Research@carle.com

The Carle Foundation Hospital
Urbana, Illinois 61801
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Rush-Copley Healthcare Center
Yorkville, Illinois 60560
Contact:
Site Public Contact
630-978-6212
Cancer.Research@rushcopley.com

Mary Greeley Medical Center
Ames, Iowa 50010
Contact:
Site Public Contact
515-956-4132

McFarland Clinic PC - Ames
Ames, Iowa 50010
Contact:
Site Public Contact
515-956-4132

McFarland Clinic PC-Boone
Boone, Iowa 50036
Contact:
Site Public Contact
515-956-4132

Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa 50325
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Mercy Cancer Center-West Lakes
Clive, Iowa 50325
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Mercy Hospital
Council Bluffs, Iowa 51503
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Greater Regional Medical Center
Creston, Iowa 50801
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa 50314
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Mercy Medical Center - Des Moines
Des Moines, Iowa 50314
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa 50501
Contact:
Site Public Contact
515-956-4132

McFarland Clinic PC-Jefferson
Jefferson, Iowa 50129
Contact:
Site Public Contact
515-956-4132

McFarland Clinic PC-Marshalltown
Marshalltown, Iowa 50158
Contact:
Site Public Contact
515-956-4132

Mercy Medical Center-West Lakes
West Des Moines, Iowa 50266
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Coffeyville Regional Medical Center
Coffeyville, Kansas 67337
Contact:
Site Public Contact
620-252-1606

Hays Medical Center
Hays, Kansas 67601
Contact:
Site Public Contact
785-623-5774

University of Kansas Cancer Center-West
Kansas City, Kansas 66112
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

University of Kansas Cancer Center
Kansas City, Kansas 66160
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

Olathe Medical Center
Olathe, Kansas 66061
Contact:
Site Public Contact
913-791-3500
Jeni.wakefield@olathehealth.org

University of Kansas Cancer Center-Overland Park
Overland Park, Kansas 66210
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

University of Kansas Hospital-Indian Creek Campus
Overland Park, Kansas 66211
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

Via Christi Hospital-Pittsburg
Pittsburg, Kansas 66762
Contact:
Site Public Contact
620-235-7900

Salina Regional Health Center
Salina, Kansas 67401
Contact:
Site Public Contact
785-452-7038
kkavoura@srhc.com

Saint Francis Hospital and Medical Center - Topeka
Topeka, Kansas 66606
Contact:
Site Public Contact
785-295-8000

University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas 66205
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

Via Christi Regional Medical Center
Wichita, Kansas 67214
Contact:
Site Public Contact
800-362-0070
Keisha.humphries@ascension.org

Flaget Memorial Hospital
Bardstown, Kentucky 40004
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Commonwealth Cancer Center-Corbin
Corbin, Kentucky 40701
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Elizabeth Medical Center South
Edgewood, Kentucky 41017
Contact:
Site Public Contact
859-301-5473
darla.hehman@stelizabeth.com

Saint Elizabeth Fort Thomas
Fort Thomas, Kentucky 41075
Contact:
Site Public Contact
859-301-9418

Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky 40504
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Joseph Hospital East
Lexington, Kentucky 40509
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Joseph London
London, Kentucky 40741
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Jewish Hospital
Louisville, Kentucky 40202
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky 40202
Contact:
Site Public Contact
502-562-3429

Saints Mary and Elizabeth Hospital
Louisville, Kentucky 40215
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Jewish Hospital Medical Center Northeast
Louisville, Kentucky 40245
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Jewish Hospital Medical Center South
Shepherdsville, Kentucky 40165
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana 70809
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Woman's Hospital
Baton Rouge, Louisiana 70817
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Mary Bird Cancer Center/Saint Tammany Parish
Covington, Louisiana 70433
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Mary Bird Perkins Cancer Center/Terrebonne General Medical Center
Houma, Louisiana 70360
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Ochsner Medical Center Jefferson
New Orleans, Louisiana 70121
Contact:
Site Public Contact
504-703-8712
Gregory.Johnstone@ochsner.org

Anne Arundel Medical Center
Annapolis, Maryland 21401
Contact:
Site Public Contact
443-481-1320
kbodenhorn@aahs.org

University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland 21201
Contact:
Site Public Contact
800-888-8823

Greater Baltimore Medical Center
Baltimore, Maryland 21204
Contact:
Site Public Contact
443-849-3706

Saint Agnes Hospital
Baltimore, Maryland 21229
Contact:
Site Public Contact
410-368-2910

Upper Chesapeake Medical Center
Bel Air, Maryland 21014
Contact:
Site Public Contact
443-643-3010

Central Maryland Radiation Oncology in Howard County
Columbia, Maryland 21044
Contact:
Site Public Contact
443-546-1300

Baltimore Washington Medical Center
Glen Burnie, Maryland 21061
Contact:
Site Public Contact
410-553-8100

Tate Cancer Center
Glen Burnie, Maryland 21061
Contact:
Site Public Contact
410-553-8100

Peninsula Regional Medical Center
Salisbury, Maryland 21801
Contact:
Site Public Contact
866-922-6237

Bronson Battle Creek
Battle Creek, Michigan 49017
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

McLaren Cancer Institute-Bay City
Bay City, Michigan 48706
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Henry Ford Cancer Institute?Downriver
Brownstown, Michigan 48183
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

McLaren Cancer Institute-Clarkston
Clarkston, Michigan 48346
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan 48038
Contact:
Site Public Contact
313-916-1784

Henry Ford Hospital
Detroit, Michigan 48202
Contact:
Site Public Contact
313-916-1784

Green Bay Oncology - Escanaba
Escanaba, Michigan 49829
Contact:
Site Public Contact
920-433-8889
Christy.Gilchrist@hshs.org

McLaren Cancer Institute-Flint
Flint, Michigan 48532
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Mercy Health Saint Mary's
Grand Rapids, Michigan 49503
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Spectrum Health at Butterworth Campus
Grand Rapids, Michigan 49503
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Bronson Methodist Hospital
Kalamazoo, Michigan 49007
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

West Michigan Cancer Center
Kalamazoo, Michigan 49007
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Borgess Medical Center
Kalamazoo, Michigan 49048
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

McLaren-Greater Lansing
Lansing, Michigan 48910
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Lapeer Region
Lapeer, Michigan 48446
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Macomb
Mount Clemens, Michigan 48043
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Central Michigan
Mount Pleasant, Michigan 48858
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Mercy Health Mercy Campus
Muskegon, Michigan 49444
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Lakeland Hospital Niles
Niles, Michigan 49120
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

McLaren Cancer Institute-Owosso
Owosso, Michigan 48867
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Northern Michigan
Petoskey, Michigan 49770
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren-Port Huron
Port Huron, Michigan 48060
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Spectrum Health Reed City Hospital
Reed City, Michigan 49677
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Lakeland Medical Center Saint Joseph
Saint Joseph, Michigan 49085
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Marie Yeager Cancer Center
Saint Joseph, Michigan 49085
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Munson Medical Center
Traverse City, Michigan 49684
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan 48322
Contact:
Site Public Contact
888-734-5322

Henry Ford Wyandotte Hospital
Wyandotte, Michigan 48192
Contact:
Site Public Contact
nhay@hfhs.org

Metro Health Hospital
Wyoming, Michigan 49519
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota 56007
Contact:
Site Public Contact
855-776-0015

Sanford Joe Lueken Cancer Center
Bemidji, Minnesota 56601
Contact:
Site Public Contact
218-333-5000

Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota 56401
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Fairview Ridges Hospital
Burnsville, Minnesota 55337
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mercy Hospital
Coon Rapids, Minnesota 55433
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Deer River Clinic
Deer River, Minnesota 56636
Contact:
Site Public Contact
218-786-3308

Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota 56501
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Essentia Health Cancer Center
Duluth, Minnesota 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's Medical Center
Duluth, Minnesota 55805
Contact:
Site Public Contact
888-203-7267

Miller-Dwan Hospital
Duluth, Minnesota 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Fairview-Southdale Hospital
Edina, Minnesota 55435
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Lake Region Healthcare Corporation-Cancer Care
Fergus Falls, Minnesota 56537
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health - Fosston
Fosston, Minnesota 56542
Contact:
Site Public Contact
701-364-6272

Unity Hospital
Fridley, Minnesota 55432
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health Hibbing Clinic
Hibbing, Minnesota 55746
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Mayo Clinic Health Systems-Mankato
Mankato, Minnesota 56001
Contact:
Site Public Contact
855-776-0015

Fairview Maple Grove Medical Center
Maple Grove, Minnesota 55369
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota 55109
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Maplewood, Minnesota 55109
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Abbott-Northwestern Hospital
Minneapolis, Minnesota 55407
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Hennepin County Medical Center
Minneapolis, Minnesota 55415
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Health Partners Inc
Minneapolis, Minnesota 55454
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Monticello Cancer Center
Monticello, Minnesota 55362
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

New Ulm Medical Center
New Ulm, Minnesota 56073
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mayo Clinic Radiation Therapy-Northfield
Northfield, Minnesota 55057
Contact:
Site Public Contact
855-776-0015

Essentia Health - Park Rapids
Park Rapids, Minnesota 56470
Contact:
Site Public Contact
701-364-6272

North Memorial Medical Health Center
Robbinsdale, Minnesota 55422
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mayo Clinic
Rochester, Minnesota 55905
Contact:
Site Public Contact
855-776-0015

Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota 55416
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Regions Hospital
Saint Paul, Minnesota 55101
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

United Hospital
Saint Paul, Minnesota 55102
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health Sandstone
Sandstone, Minnesota 55072
Contact:
Site Public Contact
701-364-6272

Saint Francis Regional Medical Center
Shakopee, Minnesota 55379
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Lakeview Hospital
Stillwater, Minnesota 55082
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Sanford Thief River Falls Medical Center
Thief River Falls, Minnesota 56701
Contact:
Site Public Contact
605-312-3320

Essentia Health Virginia Clinic
Virginia, Minnesota 55792
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Ridgeview Medical Center
Waconia, Minnesota 55387
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Rice Memorial Hospital
Willmar, Minnesota 56201
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota 55125
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Sanford Cancer Center Worthington
Worthington, Minnesota 56187
Contact:
Site Public Contact
605-312-3320

Fairview Lakes Medical Center
Wyoming, Minnesota 55092
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi 38655
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Parkland Health Center-Bonne Terre
Bonne Terre, Missouri 63628
Contact:
Site Public Contact
314-996-5569

Saint Francis Medical Center
Cape Girardeau, Missouri 63703
Contact:
Site Public Contact
573-334-2230
sfmc@sfmc.net

Southeast Cancer Center
Cape Girardeau, Missouri 63703
Contact:
Site Public Contact
573-651-5550

Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri 63141
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Capital Region Southwest Campus
Jefferson City, Missouri 65109
Contact:
Site Public Contact
573-632-4814
swooden@mail.crmc.org

Truman Medical Center
Kansas City, Missouri 64108
Contact:
Site Public Contact
816-404-4375

The University of Kansas Cancer Center-South
Kansas City, Missouri 64131
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

The University of Kansas Cancer Center-North
Kansas City, Missouri 64154
Contact:
Site Public Contact
913-945-7552
ctnursenav@kumc.edu

The University of Kansas Cancer Center-Lee's Summit
Lee's Summit, Missouri 64064
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Washington University School of Medicine
Saint Louis, Missouri 63110
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Siteman Cancer Center-South County
Saint Louis, Missouri 63129
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Missouri Baptist Medical Center
Saint Louis, Missouri 63131
Contact:
Site Public Contact
314-996-5569

Siteman Cancer Center at Saint Peters Hospital
Saint Peters, Missouri 63376
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri 63670
Contact:
Site Public Contact
314-996-5569

Missouri Baptist Sullivan Hospital
Sullivan, Missouri 63080
Contact:
Site Public Contact
314-996-5569

Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, Missouri 63127
Contact:
Site Public Contact
314-996-5569

Community Hospital of Anaconda
Anaconda, Montana 59711
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Billings Clinic Cancer Center
Billings, Montana 59101
Contact:
Site Public Contact
800-996-2663
research@billingsclinic.org

Saint Vincent Healthcare
Billings, Montana 59101
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Vincent Frontier Cancer Center
Billings, Montana 59102
Contact:
Site Public Contact
800-648-6274

Bozeman Deaconess Hospital
Bozeman, Montana 59715
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana 59405
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Great Falls Clinic
Great Falls, Montana 59405
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Peter's Community Hospital
Helena, Montana 59601
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Kalispell Regional Medical Center
Kalispell, Montana 59901
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Patrick Hospital - Community Hospital
Missoula, Montana 59802
Contact:
Site Public Contact
406-327-3118
amy.hanneman@providence.org

Community Medical Hospital
Missoula, Montana 59804
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

CHI Health Saint Francis
Grand Island, Nebraska 68803
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Heartland Hematology and Oncology
Kearney, Nebraska 68845
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

CHI Health Good Samaritan
Kearney, Nebraska 68847
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Elizabeth Regional Medical Center
Lincoln, Nebraska 68510
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Immanuel Medical Center
Omaha, Nebraska 68122
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Hematology and Oncology Consultants PC
Omaha, Nebraska 68122
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska 68124
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Lakeside Hospital
Omaha, Nebraska 68130
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Creighton University Medical Center
Omaha, Nebraska 68131
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Midlands Community Hospital
Papillion, Nebraska 68046
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Exeter Hospital
Exeter, New Hampshire 03833
Contact:
Site Public Contact
800-439-3837

Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey 07920
Contact:
Site Public Contact
212-639-7592

Saint Barnabas Medical Center
Livingston, New Jersey 07039
Contact:
Site Public Contact
973-322-2934
joanne.loeb@rwjbh.org

Memorial Sloan Kettering Monmouth
Middletown, New Jersey 07748
Contact:
Site Public Contact
212-639-7592

Memorial Sloan Kettering Bergen
Montvale, New Jersey 07645
Contact:
Site Public Contact
212-639-7592

Virtua Memorial
Mount Holly, New Jersey 08060
Contact:
Site Public Contact
609-914-6762

Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey 08903
Contact:
Site Public Contact
732-235-8675

Virtua Voorhees
Voorhees, New Jersey 08043
Contact:
Site Public Contact
856-247-7395

University of New Mexico Cancer Center
Albuquerque, New Mexico 87102
Contact:
Site Public Contact
505-925-0366
LByatt@nmcca.org

Lovelace Radiation Oncology
Albuquerque, New Mexico 87109
Contact:
Site Public Contact
505-272-0530
AYost@nmcca.org

New Mexico Oncology Hematology Consultants
Albuquerque, New Mexico 87109
Contact:
Site Public Contact
505-272-0530
CLee@nmcca.org

Hematology Oncology Associates of Central New York-Auburn
Auburn, New York 13021
Contact:
Site Public Contact
315-472-7504

Northwell Health Imbert Cancer Center
Bay Shore, New York 11706
Contact:
Site Public Contact
516-734-8896

Montefiore Medical Center-Einstein Campus
Bronx, New York 10461
Contact:
Site Public Contact
718-379-6866
aaraiza@montefiore.org

Montefiore Medical Center-Weiler Hospital
Bronx, New York 10461
Contact:
Site Public Contact
718-379-6866
aaraiza@montefiore.org

Montefiore Medical Center - Moses Campus
Bronx, New York 10467
Contact:
Site Public Contact
718-379-6866
aaraiza@montefiore.org

New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn, New York 11215
Contact:
Site Public Contact
718-780-3677
Adg9003@nyp.org

Memorial Sloan Kettering Commack
Commack, New York 11725
Contact:
Site Public Contact
212-639-7592

Hematology Oncology Associates of Central New York-East Syracuse
East Syracuse, New York 13057
Contact:
Site Public Contact
315-472-7504

Arnot Ogden Medical Center/Falck Cancer Center
Elmira, New York 14905
Contact:
Site Public Contact
607-271-7000

Memorial Sloan Kettering Westchester
Harrison, New York 10604
Contact:
Site Public Contact
212-639-7592

Northwell Health/Center for Advanced Medicine
Lake Success, New York 11042
Contact:
Site Public Contact
516-734-8896

Lenox Hill Hospital
New York, New York 10021
Contact:
Site Public Contact
516-734-8896

Columbia University/Herbert Irving Cancer Center
New York, New York 10032
Contact:
Site Public Contact
212-305-6361
nr2616@cumc.columbia.edu

Memorial Sloan Kettering Cancer Center
New York, New York 10065
Contact:
Site Public Contact
212-639-7592

Memorial Sloan Kettering Rockville Centre
Rockville Centre, New York 11570
Contact:
Site Public Contact
212-639-7592

Staten Island University Hospital
Staten Island, New York 10305
Contact:
Site Public Contact
718-226-8888

Stony Brook University Medical Center
Stony Brook, New York 11794
Contact:
Site Public Contact
800-862-2215

State University of New York Upstate Medical University
Syracuse, New York 13210
Contact:
Site Public Contact
315-464-5476

Hematology Oncology Associates of Central New York-Onondaga Hill
Syracuse, New York 13215
Contact:
Site Public Contact
315-472-7504

SUNY Upstate Medical Center-Community Campus
Syracuse, New York 13215
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Sanford Bismarck Medical Center
Bismarck, North Dakota 58501
Contact:
Site Public Contact
701-323-5760
tamara.fischer@sanfordhealth.org

Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota 58103
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Sanford South University Medical Center
Fargo, North Dakota 58103
Contact:
Site Public Contact
701-234-6161

Roger Maris Cancer Center
Fargo, North Dakota 58122
Contact:
Site Public Contact
701-234-6161

Sanford Broadway Medical Center
Fargo, North Dakota 58122
Contact:
Site Public Contact
800-437-4010

Altru Cancer Center
Grand Forks, North Dakota 58201
Contact:
Site Public Contact
701-780-6520

Essentia Health - Jamestown Clinic
Jamestown, North Dakota 58401
Contact:
Site Public Contact
701-364-6272

Cleveland Clinic Akron General
Akron, Ohio 44307
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio 44122
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Strecker Cancer Center-Belpre
Belpre, Ohio 45714
Contact:
Site Public Contact
800-523-3977
sheree@columbusccop.org

Geauga Hospital
Chardon, Ohio 44024
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Adena Regional Medical Center
Chillicothe, Ohio 45601
Contact:
Site Public Contact
877-779-7585
sheree@columbusccop.org

University of Cincinnati/Barrett Cancer Center
Cincinnati, Ohio 45219
Contact:
Site Public Contact
513-558-4553
uchealthnews@uc.edu

Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio 45220
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Bethesda North Hospital
Cincinnati, Ohio 45242
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

TriHealth Cancer Institute-Westside
Cincinnati, Ohio 45247
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

TriHealth Cancer Institute-Anderson
Cincinnati, Ohio 45255
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Case Western Reserve University
Cleveland, Ohio 44106
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio 44111
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Cleveland Clinic Foundation
Cleveland, Ohio 44195
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Ohio State University Comprehensive Cancer Center
Columbus, Ohio 43210
Contact:
Site Public Contact
800-293-5066
Jamesline@osumc.edu

Mount Carmel East Hospital
Columbus, Ohio 43213
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Columbus Oncology and Hematology Associates Inc
Columbus, Ohio 43214
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Riverside Methodist Hospital
Columbus, Ohio 43214
Contact:
Site Public Contact
614-566-4475
sheree@columbusccop.org

Grant Medical Center
Columbus, Ohio 43215
Contact:
Site Public Contact
614-566-4475
sheree@columbusccop.org

The Mark H Zangmeister Center
Columbus, Ohio 43219
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Mount Carmel Health Center West
Columbus, Ohio 43222
Contact:
Site Public Contact
614-234-5433
sheree@columbusccop.org

Doctors Hospital
Columbus, Ohio 43228
Contact:
Site Public Contact
614-566-3275
sheree@columbusccop.org

Delaware Health Center-Grady Cancer Center
Delaware, Ohio 43015
Contact:
Site Public Contact
740-615-0227
sheree@columbusccop.org

Delaware Radiation Oncology
Delaware, Ohio 43015
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Grady Memorial Hospital
Delaware, Ohio 43015
Contact:
Site Public Contact
740-615-2403
sheree@columbusccop.org

Mercy Cancer Center-Elyria
Elyria, Ohio 44035
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Cleveland Clinic Cancer Center Independence
Independence, Ohio 44131
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Fairfield Medical Center
Lancaster, Ohio 43130
Contact:
Site Public Contact
740-687-8863
sheree@columbusccop.org

OhioHealth Mansfield Hospital
Mansfield, Ohio 44903
Contact:
Site Public Contact
419-526-8018
sheree@columbusccop.org

Cleveland Clinic Cancer Center Mansfield
Mansfield, Ohio 44906
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Marietta Memorial Hospital
Marietta, Ohio 45750
Contact:
Site Public Contact
800-523-3977
sheree@columbusccop.org

OhioHealth Marion General Hospital
Marion, Ohio 43302
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio 44124
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Ireland Cancer Center Landerbrook Health Center
Mayfield Heights, Ohio 44124
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Southwest General Health Center Ireland Cancer Center
Middleburg Heights, Ohio 44130
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Knox Community Hospital
Mount Vernon, Ohio 43050
Contact:
Site Public Contact
740-393-9000
sheree@columbusccop.org

Licking Memorial Hospital
Newark, Ohio 43055
Contact:
Site Public Contact
740-348-4000
sheree@columbusccop.org

Newark Radiation Oncology
Newark, Ohio 43055
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Southern Ohio Medical Center
Portsmouth, Ohio 45662
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

University Hospitals Portage Medical Center
Ravenna, Ohio 44266
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Ireland Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio 44870
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

North Coast Cancer Care
Sandusky, Ohio 44870
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Cleveland Clinic Cancer Center Strongsville
Strongsville, Ohio 44136
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

University Pointe
West Chester, Ohio 45069
Contact:
Site Public Contact
clinicaltrials@ucphysicians.com

Saint Ann's Hospital
Westerville, Ohio 43081
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

UHHS-Westlake Medical Center
Westlake, Ohio 44145
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, Ohio 44691
Contact:
Site Public Contact
866-223-8100
CancerAnswer@ccf.org

Genesis Healthcare System Cancer Care Center
Zanesville, Ohio 43701
Contact:
Site Public Contact
740-454-5232
sheree@columbusccop.org

University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma 73104
Contact:
Site Public Contact
405-271-8777
ou-clinical-trials@ouhsc.edu

Saint Charles Health System
Bend, Oregon 97701
Contact:
Site Public Contact
541-706-2909
nosall@stcharleshealthcare.org

Clackamas Radiation Oncology Center
Clackamas, Oregon 97015
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Providence Oncology and Hematology Care Southeast
Clackamas, Oregon 97015
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Bay Area Hospital
Coos Bay, Oregon 97420
Contact:
Site Public Contact
541-269-8392
cherie.cox@bayareahospital.org

Legacy Mount Hood Medical Center
Gresham, Oregon 97030
Contact:
Site Public Contact
503-413-2150

Providence Newberg Medical Center
Newberg, Oregon 97132
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon 97210
Contact:
Site Public Contact
800-220-4937
cancer@lhs.org

Providence Portland Medical Center
Portland, Oregon 97213
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Providence Saint Vincent Medical Center
Portland, Oregon 97225
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Saint Charles Health System-Redmond
Redmond, Oregon 97756
Contact:
Site Public Contact
541-706-2909

Legacy Meridian Park Hospital
Tualatin, Oregon 97062
Contact:
Site Public Contact
503-413-1742

UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania 15009
Contact:
Site Public Contact
724-773-7616

Saint Luke's University Hospital-Bethlehem Campus
Bethlehem, Pennsylvania 18015
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania 19317
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Geisinger Medical Center
Danville, Pennsylvania 17822
Contact:
Site Public Contact
570-271-5251
HemonCCTrials@geisinger.edu

Ephrata Cancer Center
Ephrata, Pennsylvania 17522
Contact:
Site Public Contact
717-721-4840

Ephrata Community Hospital
Ephrata, Pennsylvania 17522
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

UPMC Cancer Center at UPMC Horizon
Farrell, Pennsylvania 16121
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Adams Cancer Center
Gettysburg, Pennsylvania 17325
Contact:
Site Public Contact
877-441-7957

UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania 15601
Contact:
Site Public Contact
724-838-1900

Cherry Tree Cancer Center
Hanover, Pennsylvania 17331
Contact:
Site Public Contact
877-441-7957

Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania 18201
Contact:
Site Public Contact
570-459-2901
HemonCCTrials@geisinger.edu

UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania 15901
Contact:
Site Public Contact
814-534-4724

Sechler Family Cancer Center
Lebanon, Pennsylvania 17042
Contact:
Site Public Contact
717-741-8303
doxenberg@wellspan.org

Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania 17837
Contact:
Site Public Contact
570-374-8555
HemonCCTrials@geisinger.edu

Lewistown Hospital
Lewistown, Pennsylvania 17044
Contact:
Site Public Contact
717-242-7703
HemonCCTrials@geisinger.edu

UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania 15132
Contact:
Site Public Contact
412-647-8073

Holy Redeemer Hospital and Medical Center
Meadowbrook, Pennsylvania 19046
Contact:
Site Public Contact
215-938-3551

UPMC Cancer Center - Monroeville
Monroeville, Pennsylvania 15146
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

UPMC-Coraopolis/Heritage Valley Radiation Oncology
Moon, Pennsylvania 15108
Contact:
Site Public Contact
412-604-2020

UPMC Jameson
New Castle, Pennsylvania 16105
Contact:
Site Public Contact
724-656-5870

UPMC-Magee Womens Hospital
Pittsburgh, Pennsylvania 15213
Contact:
Site Public Contact
412-647-2811

UPMC-Saint Margaret
Pittsburgh, Pennsylvania 15215
Contact:
Site Public Contact
412-784-4900

UPMC-Shadyside Hospital
Pittsburgh, Pennsylvania 15232
Contact:
Site Public Contact
412-621-2334

UPMC-Passavant Hospital
Pittsburgh, Pennsylvania 15237
Contact:
Site Public Contact
412-367-6454

UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania 15243
Contact:
Site Public Contact
412-502-3920

Guthrie Medical Group PC-Robert Packer Hospital
Sayre, Pennsylvania 18840
Contact:
Site Public Contact
800-836-0388

Community Medical Center
Scranton, Pennsylvania 18510
Contact:
Site Public Contact
570-703-4768
HemonCCTrials@geisinger.edu

UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania 16346
Contact:
Site Public Contact
814-676-7900

UPMC Uniontown Hospital Radiation Oncology
Uniontown, Pennsylvania 15401
Contact:
Site Public Contact
724-437-2503

UPMC Washington Hospital Radiation Oncology
Washington, Pennsylvania 15301
Contact:
Site Public Contact
724-223-3788
cancer@washingtonhospital.org

Reading Hospital
West Reading, Pennsylvania 19611
Contact:
Site Public Contact
610-988-9323

Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania 18711
Contact:
Site Public Contact
570-271-5251
HemonCCTrials@geisinger.edu

WellSpan Health-York Cancer Center
York, Pennsylvania 17403
Contact:
Site Public Contact
877-441-7957

WellSpan Health-York Hospital
York, Pennsylvania 17403
Contact:
Site Public Contact
877-441-7957

Medical University of South Carolina
Charleston, South Carolina 29425
Contact:
Site Public Contact
843-792-9321
hcc-clinical-trials@musc.edu

Greenville Health System Cancer Institute-Faris
Greenville, South Carolina 29605
Contact:
Site Public Contact
864-241-6251
kwilliams8@ghs.org

Greenville Health System Cancer Institute-Eastside
Greenville, South Carolina 29615
Contact:
Site Public Contact
864-241-6251
kwilliams8@ghs.org

Greenville Health System Cancer Institute-Greer
Greer, South Carolina 29650
Contact:
Site Public Contact
864-241-6251
kwilliams8@ghs.org

The Radiation Oncology Center-Hilton Head/Bluffton
Hilton Head Island, South Carolina 29926
Contact:
Site Public Contact
912-819-5704
underberga@sjchs.org

Greenville Health System Cancer Institute-Seneca
Seneca, South Carolina 29672
Contact:
Site Public Contact
864-241-6251
kwilliams8@ghs.org

Greenville Health System Cancer Institute-Spartanburg
Spartanburg, South Carolina 29307
Contact:
Site Public Contact
864-241-6251
kwilliams8@ghs.org

Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota 57104
Contact:
Site Public Contact
605-312-3320

Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota 57117-5134
Contact:
Site Public Contact
605-312-3320
OncologyClinicalTrialsSF@SanfordHealth.org

Wellmont Bristol Regional Medical Center
Bristol, Tennessee 37620
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Erlanger Medical Center
Chattanooga, Tennessee 37403
Contact:
Site Public Contact
423-778-6947

Memorial Hospital
Chattanooga, Tennessee 37404
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Pulmonary Medicine Center of Chattanooga-Hixson
Hixson, Tennessee 37343
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Wellmont Medical Associates Oncology and Hematology-Johnson City
Johnson City, Tennessee 37604
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Wellmont Holston Valley Hospital and Medical Center
Kingsport, Tennessee 37660
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Wellmont Medical Associates Oncology and Hematology-Kingsport
Kingsport, Tennessee 37660
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee 38120
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Memorial GYN Plus
Ooltewah, Tennessee 37363
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Joseph Regional Cancer Center
Bryan, Texas 77802
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork, Utah 84003
Contact:
Site Public Contact
801-855-4100
officeofresearch@imail.org

Sandra L Maxwell Cancer Center
Cedar City, Utah 84720
Contact:
Site Public Contact
435-868-5680
officeofresearch@imail.org

Farmington Health Center
Farmington, Utah 84025
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

Logan Regional Hospital
Logan, Utah 84321
Contact:
Site Public Contact
435-716-6400
officeofresearch@imail.org

Intermountain Medical Center
Murray, Utah 84107
Contact:
Site Public Contact
801-507-3950
officeofresearch@imail.org

McKay-Dee Hospital Center
Ogden, Utah 84403
Contact:
Site Public Contact
801-387-7426
officeofresearch@imail.org

Utah Valley Regional Medical Center
Provo, Utah 84604
Contact:
Site Public Contact
801-357-7965
officeofresearch@imail.org

Riverton Hospital
Riverton, Utah 84065
Contact:
Site Public Contact
801-507-3950
officeofresearch@imail.org

Dixie Medical Center Regional Cancer Center
Saint George, Utah 84770
Contact:
Site Public Contact
435-688-4167
officeofresearch@imail.org

Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah 84106
Contact:
Site Public Contact
801-933-6070
officeofresearch@imail.org

Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah 84112
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

LDS Hospital
Salt Lake City, Utah 84143
Contact:
Site Public Contact
801-408-1347
officeofresearch@imail.org

South Jordan Health Center
South Jordan, Utah 84009
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

Wellmont Medical Associates-Bristol
Bristol, Virginia 24201
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

IMG Hematology Oncology 8501
Fairfax, Virginia 22031
Contact:
Site Public Contact
703-720-5210
Stephanie.VanBebber@inova.org

Inova Fair Oaks Hospital
Fairfax, Virginia 22033
Contact:
Site Public Contact
703-720-5210
Stephanie.VanBebber@inova.org

Inova Fairfax Hospital
Falls Church, Virginia 22042
Contact:
Site Public Contact
703-208-6650
Stephanie.VanBebber@inova.org

Southwest VA Regional Cancer Center
Norton, Virginia 24273
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Inova Breast Surgery Fairfax
Woodbridge, Virginia 22031
Contact:
Site Public Contact
Stephanie.VanBebber@inova.org

Providence Regional Cancer System-Aberdeen
Aberdeen, Washington 98520
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

PeaceHealth Saint Joseph Medical Center
Bellingham, Washington 98225
Contact:
Site Public Contact
360-715-4133
mjohnson9@peacehealth.org

Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington 98310
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Harrison Medical Center
Bremerton, Washington 98310
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Highline Medical Center-Main Campus
Burien, Washington 98166
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Providence Regional Cancer System-Centralia
Centralia, Washington 98531
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Swedish Medical Center-Edmonds
Edmonds, Washington 98026
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Saint Elizabeth Hospital
Enumclaw, Washington 98022
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Providence Regional Cancer Partnership
Everett, Washington 98201
Contact:
Site Public Contact
425-261-3529
marilyn.birchman@providence.org

Saint Francis Hospital
Federal Way, Washington 98003
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Swedish Cancer Institute-Issaquah
Issaquah, Washington 98029
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Kadlec Clinic Hematology and Oncology
Kennewick, Washington 99336
Contact:
Site Public Contact
509-783-4637
research@kadlecmed.org

Providence Regional Cancer System-Lacey
Lacey, Washington 98503
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Saint Clare Hospital
Lakewood, Washington 98499
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

PeaceHealth Saint John Medical Center
Longview, Washington 98632
Contact:
Site Public Contact
360-514-2016
kmakin-bond@peacehealth.org

Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, Washington 98370
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Pacific Gynecology Specialists
Seattle, Washington 98104
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-Ballard Campus
Seattle, Washington 98107
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Kaiser Permanente Washington
Seattle, Washington 98112
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-First Hill
Seattle, Washington 98122-4307
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-Cherry Hill
Seattle, Washington 98122-5711
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

PeaceHealth United General Medical Center
Sedro-Woolley, Washington 98284
Contact:
Site Public Contact
360-788-8240

Providence Regional Cancer System-Shelton
Shelton, Washington 98584
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Franciscan Research Center-Northwest Medical Plaza
Tacoma, Washington 98405
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Northwest Medical Specialties PLLC
Tacoma, Washington 98405
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

PeaceHealth Southwest Medical Center
Vancouver, Washington 98664
Contact:
Site Public Contact
360-514-3940
kmakin-bond@peacehealth.org

Legacy Salmon Creek Hospital
Vancouver, Washington 98686
Contact:
Site Public Contact
503-413-2150

Providence Saint Mary Regional Cancer Center
Walla Walla, Washington 99362
Contact:
Site Public Contact
509-897-5993
Cheryl.Dodd@providence.org

Providence Regional Cancer System-Yelm
Yelm, Washington 98597
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Ashland Memorial Medical Center
Ashland, Wisconsin 54806
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

Duluth Clinic Ashland
Ashland, Wisconsin 54806
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Wheaton Franciscan Healthcare-Elmbrook Memorial Hospital
Brookfield, Wisconsin 53045
Contact:
Site Public Contact
262-785-2273

Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin 54701
Contact:
Site Public Contact
855-776-0015

Saint Agnes Hospital/Agnesian Cancer Center
Fond Du Lac, Wisconsin 54935
Contact:
Site Public Contact
800-494-2927

Wheaton Franciscan Healthcare-Saint Francis/Reiman Cancer Center
Franklin, Wisconsin 53132
Contact:
Site Public Contact
262-785-2273

Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin 54301
Contact:
Site Public Contact
920-433-8889
Christy.Gilchrist@hshs.org

Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin 54303
Contact:
Site Public Contact
773-702-9171
protocols@AllianceNCTN.org

UW Cancer Center Johnson Creek
Johnson Creek, Wisconsin 53038
Contact:
Site Public Contact
920-699-3500
lynda.persico@uwmf.wisc.edu

Gundersen Lutheran Medical Center
La Crosse, Wisconsin 54601
Contact:
Site Public Contact
608-775-2385
cancerctr@gundersenhealth.org

Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin 54601
Contact:
Site Public Contact
855-776-0015

University of Wisconsin Hospital and Clinics
Madison, Wisconsin 53792
Contact:
Site Public Contact
800-622-8922

Holy Family Memorial Hospital
Manitowoc, Wisconsin 54221
Contact:
Site Public Contact
920-320-2749

Saint Vincent Hospital Cancer Center at Marinette
Marinette, Wisconsin 54143
Contact:
Site Public Contact
920-433-8889
Christy.Gilchrist@hshs.org

Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin 53226
Contact:
Site Public Contact
414-805-4380

Cancer Center of Western Wisconsin
New Richmond, Wisconsin 54017
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Green Bay Oncology - Oconto Falls
Oconto Falls, Wisconsin 54154
Contact:
Site Public Contact
920-433-8889
Christy.Gilchrist@hshs.org

Wheaton Franciscan Cancer Care - All Saints
Racine, Wisconsin 53405
Contact:
Site Public Contact
262-785-2273

HSHS Saint Nicholas Hospital
Sheboygan, Wisconsin 53081
Contact:
Site Public Contact
920-433-8889
Christy.Gilchrist@hshs.org

Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin 54235-1495
Contact:
Site Public Contact
920-433-8889
Christy.Gilchrist@hshs.org

Aspirus UW Cancer Center
Wisconsin Rapids, Wisconsin 54494
Contact:
Site Public Contact
715-422-7718

Cheyenne Regional Medical Center-West
Cheyenne, Wyoming 82001
Contact:
Site Public Contact
303-777-2663
ccrp@co-cancerresearch.org

Billings Clinic-Cody
Cody, Wyoming 82414
Contact:
Site Public Contact
800-996-2663
research@billingsclinic.org

Welch Cancer Center
Sheridan, Wyoming 82801
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

More Details

NCT ID
NCT03414970
Status
Recruiting
Sponsor
Alliance for Clinical Trials in Oncology

Study Contact

Matthew Poppe, MD
801-581-8793
Matthew.Poppe@hci.utah.edu

Detailed Description

PRIMARY OBJECTIVES:

I. To evaluate whether the reconstruction complication rate at 24 months post radiation is non-inferior with hypofractionation.

SECONDARY OBJECTIVES:

I. To evaluate the incidence of acute and late radiation complications, based on Common Terminology Criteria for Adverse Events (CTCAE) 4.0 toxicity.

II. To evaluate the local and local regional recurrence rate. III. To compare reconstruction complication rates based on reconstruction method (autologous +/- implant versus [vs] implant only) and timing of reconstruction received (immediate vs. intent for delayed).

TERTIARY OBJECTIVES:

I. To evaluate reconstructed breast photographic cosmetic scores with hypofractionated radiation compared to standard fractionation 24 months after radiation.

II. To evaluate reconstructed breast photographic cosmetic scores 24 months after radiation based on the method and timing of reconstruction received.

III. To estimate the incidence of arm lymphedema by treatment arm. IV. To compare physical well-being, psychosocial well-being, sexual well-being, satisfaction with breast/nipples/abdomen, and satisfaction with overall outcome between the treatment arms at 24 months after radiation.

V. To estimate patient satisfaction with trial participation by treatment arm as measured by the Was It Worth It Questionnaire at 24 months after radiation.

VI. To compare the direct and indirect patient costs for radiation therapy by treatment arm.

VII. To compare patient reported total health care service utilization 12 months after the completion of radiation.

VIII. To compare the economic impact of treatment. IX. To analyze polymorphisms in MDM2 and in genes including TP53, ATM, TGFB1, IL4, IL6, and IL10 and determine correlations with a higher likelihood of adverse radiation reactions (radiation sensitivity) and with toxicities.

X. To analyze polymorphisms in MDM2 and in genes including TP53, ATM, TGFB1, IL4, IL6, and IL10 to determine correlations with secondary endpoints such as local-regional control.

OUTLINE: Patients are randomized to 1 of 2 groups.

GROUP I: Patients undergo radiation therapy daily on Monday-Friday for 5-6 weeks.

GROUP II: Patients undergo hypofractionated radiation therapy daily on Monday-Friday for 3-4 weeks.

After completion of study, patients are followed up for 5 years.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.