UAMS - Translational Research Institute

For Participant Selection: - Participant has any clinically documented sign(s) and/or symptom(s) consistent with an Inherited Retinal Disease (IRD), or asymptomatic with documented retinal changes detected by imaging or electrophysiology - Participant has documented genetic variant(s) (known pathogenic, likely pathogenic, or variants of uncertain significance) in relevant genes for any of the following IRDs: X-Linked Retinitis Pigmentosa (XLRP) and/or Achromatopsia (ACHM) - Participant or legally acceptable representative has provided informed consent (and participant assent, when applicable) in accordance with local requirements - Participant is able to have relevant visual and/or retinal assessments performed For Caregiver Selection: - Caregiver has consent from the associated participant to participate in the study, or participant assent and consent from their legally acceptable representative - Male or female aged greater than or equal to (>=)18 years - Identified by an enrolled participant (or their legally acceptable representative*) as a primary caregiver - Caregiver has provided informed consent in accordance with local requirements

For Participant Selection: - Participant has received a treatment in an IRD-related interventional trial, or is being screened for an IRD-related interventional trial For Caregiver Selection: - Caregiver has an IRD diagnosis and presents with symptoms (visual impairment)