Purpose

This phase III trial studies how well gemcitabine hydrochloride and cisplatin given with or without nab-paclitaxel work in treating patients with newly diagnosed biliary tract cancers that have spread to other places in the body. Drugs used in chemotherapy, such as gemcitabine hydrochloride, cisplatin, and nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not known if giving gemcitabine hydrochloride and cisplatin with or without nab-paclitaxel may work better at treating biliary tract cancers.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Criteria


Inclusion Criteria:

- Patients must have histologically or cytologically confirmed intrahepatic
cholangiocarcinoma, extrahepatic cholangiocarcinoma, or gallbladder cancer

- NOTE: Pathology report must be uploaded in Rave. Histology report must be
consistent with an adenocarcinoma with pancreaticobiliary primary assuming there
are no pancreatic lesions and other primaries are ruled out per local standard

- Patients must have documented metastatic or locally advanced unresectable disease on
computed tomography (CT) or magnetic resonance (MR) imaging CT scans or MRIs used to
assess measurable disease. Must have been completed within 28 days prior to
registration. CT scans or MRIs used to assess non-measurable disease must have been
completed within 42 days prior to registration. All disease must be assessed and
documented on the Baseline Tumor Assessment Form

- Patient must not have a current diagnosis of ampullary cancer

- Patients must not have received prior systemic therapy for the current metastatic or
locally advanced biliary cancer

- Patient must not have received adjuvant therapy within 6 months prior to registration

- Patients must have a complete medical history and physical exam within 28 days prior
to registration

- Patients must have a Zubrod performance status of 0 or 1

- Patients must not have a history of peripheral neuropathy of grade 2 or greater by
Common Terminology Criteria for Adverse Events (CTCAE) 5.0. In CTCAE version 5.0 grade
2 sensory neuropathy is defined as ?moderate symptoms; limiting instrumental
activities of daily living (ADLs)?

- Absolute neutrophil count (ANC) >= 1,500/mcL (obtained within 28 days prior to
registration)

- Platelets >= 100,000/mcL (obtained within 28 days prior to registration)

- Hemoglobin >= 8 g/dL (obtained within 28 days prior to registration)

- Serum albumin >= 2.8 g/dL (obtained within 28 days prior to registration)

- Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (except patients
with Gilbert?s syndrome, who must have a direct bilirubin < 1.5 mg/dL) (obtained
within 28 days prior to registration)

- Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) and
serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) =< 8 x
IULN (obtained within 28 days prior to registration)

- Serum creatinine =< IULN OR calculated creatinine clearance >= 60 mL/min (obtained
within 28 days prior to registration)

- Patients must have CA19-9 obtained within 42 days prior to registration

- Patients must have sodium, potassium, bicarbonate, chloride, blood urea nitrogen
(BUN), calcium, total protein, magnesium, and alkaline phosphatase obtained within 28
days prior to registration

- Patients must not have an active infection requiring systemic therapy

- No other prior malignancy is allowed except for the following: adequately treated
basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated
stage I or II cancer from which the patient is currently in complete remission, or any
other cancer from which the patient has been disease free for two years

- Patients must not be pregnant or nursing. Women/men of reproductive potential must
have agreed to use an effective contraceptive method. A woman is considered to be of
"reproductive potential" if she has had menses at any time in the preceding 12
consecutive months. In addition to routine contraceptive methods, "effective
contraception" also includes heterosexual celibacy and surgery intended to prevent
pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy,
bilateral oophorectomy or bilateral tubal ligation. However, if at any point a
previously celibate patient chooses to become heterosexually active during the time
period for use of contraceptive measures outlined in the protocol, he/she is
responsible for beginning contraceptive measures

- Sites must seek additional patient consent for the future use of specimens

- Patients must be informed of the investigational nature of this study and must sign
and give written informed consent in accordance with institutional and federal
guidelines

- As a part of the Oncology Patient Enrollment Network (OPEN) registration process the
treating institution's identity is provided in order to ensure that the current
(within 365 days) date of institutional review board approval for this study has been
entered in the system

Study Design

Phase
Phase 3
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Arm I (nab-paclitaxel, cisplatin, gemcitabine hydrochloride)
Patients receive nab-paclitaxel IV over 30 minutes, cisplatin IV over 60 minutes, and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.
  • Drug: Cisplatin
    Given IV
    Other names:
    • Abiplatin
    • Blastolem
    • Briplatin
    • CDDP
    • Cis-diammine-dichloroplatinum
    • Cis-diamminedichloridoplatinum
    • Cis-diamminedichloro Platinum (II)
    • Cis-diamminedichloroplatinum
    • Cis-dichloroammine Platinum (II)
    • Cis-platinous Diamine Dichloride
    • Cis-platinum
    • Cis-platinum II
    • Cis-platinum II Diamine Dichloride
    • Cismaplat
    • Cisplatina
    • Cisplatinum
    • Cisplatyl
    • Citoplatino
    • Citosin
    • Cysplatyna
    • DDP
    • Lederplatin
    • Metaplatin
    • Neoplatin
    • Peyrone's Chloride
    • Peyrone's Salt
    • Placis
    • Plastistil
    • Platamine
    • Platiblastin
    • Platiblastin-S
    • Platinex
    • Platinol
    • Platinol- AQ
    • Platinol-AQ
    • Platinol-AQ VHA Plus
    • Platinoxan
    • Platinum
    • Platinum Diamminodichloride
    • Platiran
    • Platistin
    • Platosin
  • Drug: Gemcitabine Hydrochloride
    Given IV
    Other names:
    • dFdCyd
    • Difluorodeoxycytidine Hydrochloride
    • Gemzar
    • LY-188011
    • LY188011
  • Drug: Nab-paclitaxel
    Given IV
    Other names:
    • ABI 007
    • ABI-007
    • Abraxane
    • Albumin-bound Paclitaxel
    • Albumin-Stabilized Nanoparticle Paclitaxel
    • Nanoparticle Albumin-bound Paclitaxel
    • Nanoparticle Paclitaxel
    • paclitaxel albumin-stabilized nanoparticle formulation
    • Protein-bound Paclitaxel
Experimental
Arm II (cisplatin, gemcitabine hydrochloride)
Patients receive cisplatin IV over 60 minutes and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.
  • Drug: Cisplatin
    Given IV
    Other names:
    • Abiplatin
    • Blastolem
    • Briplatin
    • CDDP
    • Cis-diammine-dichloroplatinum
    • Cis-diamminedichloridoplatinum
    • Cis-diamminedichloro Platinum (II)
    • Cis-diamminedichloroplatinum
    • Cis-dichloroammine Platinum (II)
    • Cis-platinous Diamine Dichloride
    • Cis-platinum
    • Cis-platinum II
    • Cis-platinum II Diamine Dichloride
    • Cismaplat
    • Cisplatina
    • Cisplatinum
    • Cisplatyl
    • Citoplatino
    • Citosin
    • Cysplatyna
    • DDP
    • Lederplatin
    • Metaplatin
    • Neoplatin
    • Peyrone's Chloride
    • Peyrone's Salt
    • Placis
    • Plastistil
    • Platamine
    • Platiblastin
    • Platiblastin-S
    • Platinex
    • Platinol
    • Platinol- AQ
    • Platinol-AQ
    • Platinol-AQ VHA Plus
    • Platinoxan
    • Platinum
    • Platinum Diamminodichloride
    • Platiran
    • Platistin
    • Platosin
  • Drug: Gemcitabine Hydrochloride
    Given IV
    Other names:
    • dFdCyd
    • Difluorodeoxycytidine Hydrochloride
    • Gemzar
    • LY-188011
    • LY188011

Recruiting Locations

Anchorage Associates in Radiation Medicine
Anchorage, Alaska 98508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Anchorage Radiation Therapy Center
Anchorage, Alaska 99504
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Breast Care and Surgery LLC
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Oncology and Hematology LLC
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Alaska Women's Cancer Care
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Anchorage Oncology Centre
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Katmai Oncology Group
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

Providence Alaska Medical Center
Anchorage, Alaska 99508
Contact:
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org

CTCA at Western Regional Medical Center
Goodyear, Arizona 85338
Contact:
Site Public Contact
623-207-3000

Kingman Regional Medical Center
Kingman, Arizona 86401
Contact:
Site Public Contact
protocols@swog.org

Mayo Clinic Hospital
Phoenix, Arizona 85054
Contact:
Site Public Contact
855-776-0015

Mayo Clinic in Arizona
Scottsdale, Arizona 85259
Contact:
Site Public Contact
855-776-0015

University of Arizona Cancer Center-Orange Grove Campus
Tucson, Arizona 85704
Contact:
Site Public Contact
520-694-8900

Banner University Medical Center - Tucson
Tucson, Arizona 85719
Contact:
Site Public Contact
aselegue@email.arizona.edu

University of Arizona Cancer Center-North Campus
Tucson, Arizona 85719
Contact:
Site Public Contact
800-327-2873

Mercy Hospital Fort Smith
Fort Smith, Arkansas 72903
Contact:
Site Public Contact
800-378-9373

CHI Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas 71913
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas 72401
Contact:
Site Public Contact
870-936-7067
Dawn.Smith@BMHCC.org

University of Arkansas for Medical Sciences
Little Rock, Arkansas 72205
Contact:
Site Public Contact
501-686-8274

PCR Oncology
Arroyo Grande, California 93420
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California 91505
Contact:
Site Public Contact
818-847-4793
Najee.Boucher@providence.org

City of Hope Corona
Corona, California 92879
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

City of Hope Comprehensive Cancer Center
Duarte, California 91010
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

Los Angeles County-USC Medical Center
Los Angeles, California 90033
Contact:
Site Public Contact
323-865-0451

USC / Norris Comprehensive Cancer Center
Los Angeles, California 90033
Contact:
Site Public Contact
323-865-0451

Fremont - Rideout Cancer Center
Marysville, California 95901
Contact:
Site Public Contact
530-749-4400

City of Hope Mission Hills
Mission Hills, California 91345
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California 92663
Contact:
Site Public Contact
323-865-0451

University of California Davis Comprehensive Cancer Center
Sacramento, California 95817
Contact:
Site Public Contact
916-734-3089

Salinas Valley Memorial
Salinas, California 93901
Contact:
Site Public Contact
831-759-1838
tnielsen2@svmh.com

UCSF Medical Center-Mission Bay
San Francisco, California 94158
Contact:
Site Public Contact
877-827-3222

City of Hope - Santa Clarita
Santa Clarita, California 91355
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

City of Hope South Pasadena
South Pasadena, California 91030
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California 96161
Contact:
Site Public Contact
530-582-6450

City of Hope Upland
Upland, California 91786
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

City of Hope West Covina
West Covina, California 91790
Contact:
Site Public Contact
800-826-4673
becomingapatient@coh.org

Penrose-Saint Francis Healthcare
Colorado Springs, Colorado 80907
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado 80907
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Porter Adventist Hospital
Denver, Colorado 80210
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Mercy Medical Center
Durango, Colorado 81301
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Southwest Oncology PC
Durango, Colorado 81301
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Anthony Hospital
Lakewood, Colorado 80228
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Littleton Adventist Hospital
Littleton, Colorado 80122
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Longmont United Hospital
Longmont, Colorado 80501
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado 80501
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Parker Adventist Hospital
Parker, Colorado 80138
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Mary Corwin Medical Center
Pueblo, Colorado 81004
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut 06418
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut 06824
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Yale-New Haven Shoreline Medical Center
Guilford, Connecticut 06437
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut 06105
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Center/Yale-New Haven Hospital
New Haven, Connecticut 06510
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Yale University
New Haven, Connecticut 06520
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut 06473
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Hospital-Orange Care Center
Orange, Connecticut 06477
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut 06790
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut 06611
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut 06708
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Lawrence and Memorial Cancer Center
Waterford, Connecticut 06385
Contact:
Site Public Contact
203-785-5702
canceranswers@yale.edu

Beebe Medical Center
Lewes, Delaware 19958
Contact:
Site Public Contact
302-645-3770
Dmiskin@Beebehealthcare.org

Delaware Clinical and Laboratory Physicians PA
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Helen F Graham Cancer Center
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Medical Oncology Hematology Consultants PA
Newark, Delaware 19713
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Christiana Care Health System-Christiana Hospital
Newark, Delaware 19718
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Beebe Health Campus
Rehoboth Beach, Delaware 19971
Contact:
Site Public Contact
302-645-3100
Dmiskin@Beebehealthcare.org

Nanticoke Memorial Hospital
Seaford, Delaware 19973
Contact:
Site Public Contact
302-645-3100
Dmiskin@Beebehealthcare.org

Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware 19801
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

AdventHealth Altamonte
Altamonte Springs, Florida 32701
Contact:
Site Public Contact
407-303-2200

Mayo Clinic in Florida
Jacksonville, Florida 32224-9980
Contact:
Site Public Contact
855-776-0015

AdventHealth Kissimmee
Kissimmee, Florida 34744
Contact:
Site Public Contact
407-846-4343

AdventHealth Medical Group Urology at Orlando
Orlando, Florida 32803
Contact:
Site Public Contact
407-897-3499

AdventHealth Orlando
Orlando, Florida 32803
Contact:
Site Public Contact
407-303-2090
FH.Cancer.Research@flhosp.org

AdventHealth East Orlando
Orlando, Florida 32822
Contact:
Site Public Contact
407-303-8110

AdventHealth Winter Park
Winter Park, Florida 32792
Contact:
Site Public Contact
407-646-7000

Hawaii Cancer Care - Savio
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-539-2273

Hawaii Oncology Inc-Pali Momi
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-487-7447

Pali Momi Medical Center
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-486-6000

The Cancer Center of Hawaii-Pali Momi
'Aiea, Hawaii 96701
Contact:
Site Public Contact
808-678-9000

Hawaii Cancer Care Inc-POB II
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-524-6115

Hawaii Oncology Inc-POB I
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-532-0315

Island Urology
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-536-2306
virginia@cc.hawaii.edu

Queen's Medical Center
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-545-8548

Straub Clinic and Hospital
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-522-4333

University of Hawaii Cancer Center
Honolulu, Hawaii 96813
Contact:
Site Public Contact
808-586-2979

Hawaii Cancer Care Inc-Liliha
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-536-4888

Hawaii Oncology Inc-Kuakini
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-531-8521

Kuakini Medical Center
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-547-9816

The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii 96817
Contact:
Site Public Contact
808-547-6881

Kapiolani Medical Center for Women and Children
Honolulu, Hawaii 96826
Contact:
Site Public Contact
808-983-6090

Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii 96766
Contact:
Site Public Contact
808-535-7960

Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho 83706
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Luke's Mountain States Tumor Institute
Boise, Idaho 83712
Contact:
Site Public Contact
208-381-2774
eslinget@slhs.org

Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho 83605
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Kootenai Medical Center
Coeur d'Alene, Idaho 83814
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Walter Knox Memorial Hospital
Emmett, Idaho 83617
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Luke's Mountain States Tumor Institute - Fruitland
Fruitland, Idaho 83619
Contact:
Site Public Contact
208-381-8059
hallsc@slhs.org

Idaho Urologic Institute-Meridian
Meridian, Idaho 83642
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Luke's Mountain States Tumor Institute - Meridian
Meridian, Idaho 83642
Contact:
Site Public Contact
208-381-8059
hallsc@slhs.org

Saint Alphonsus Medical Center-Nampa
Nampa, Idaho 83686
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Luke's Mountain States Tumor Institute - Nampa
Nampa, Idaho 83686
Contact:
Site Public Contact
208-381-8059
hallsc@slhs.org

Kootenai Cancer Center
Post Falls, Idaho 83854
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Kootenai Cancer Clinic
Sandpoint, Idaho 83864
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Luke's Mountain States Tumor Institute-Twin Falls
Twin Falls, Idaho 83301
Contact:
Site Public Contact
208-381-8059
hallsc@slhs.org

Rush - Copley Medical Center
Aurora, Illinois 60504
Contact:
Site Public Contact
630-978-6212
Cancer.Research@rushcopley.com

Illinois CancerCare-Bloomington
Bloomington, Illinois 61704
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Canton
Canton, Illinois 61520
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Memorial Hospital of Carbondale
Carbondale, Illinois 62902
Contact:
Site Public Contact
618-457-5200
clinical.research@sih.net

SIH Cancer Institute
Carterville, Illinois 62918
Contact:
Site Public Contact
618-985-3333
clinical.research@sih.net

Illinois CancerCare-Carthage
Carthage, Illinois 62321
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Centralia Oncology Clinic
Centralia, Illinois 62801
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Northwestern University
Chicago, Illinois 60611
Contact:
Site Public Contact
312-695-1301
cancer@northwestern.edu

University of Illinois
Chicago, Illinois 60612
Contact:
Site Public Contact
312-355-3046

Carle on Vermilion
Danville, Illinois 61832
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois 62526
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Decatur Memorial Hospital
Decatur, Illinois 62526
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Illinois CancerCare-Dixon
Dixon, Illinois 61021
Contact:
Site Public Contact
815-285-7800

Carle Physician Group-Effingham
Effingham, Illinois 62401
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Crossroads Cancer Center
Effingham, Illinois 62401
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Illinois CancerCare-Eureka
Eureka, Illinois 61530
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Galesburg
Galesburg, Illinois 61401
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Western Illinois Cancer Treatment Center
Galesburg, Illinois 61401
Contact:
Site Public Contact
309-344-2831

Northwestern Medicine Cancer Center Delnor
Geneva, Illinois 60134
Contact:
Site Public Contact
630-315-1918
Claudine.Gamster@CadenceHealth.org

Joliet Oncology-Hematology Associates Limited
Joliet, Illinois 60435
Contact:
Site Public Contact
815-730-3098
maureenc@jolietoncology.com

Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois 61443
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois 60045
Contact:
Site Public Contact
cancertrials@northwestern.edu

Illinois CancerCare-Macomb
Macomb, Illinois 61455
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois 61938
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Good Samaritan Regional Health Center
Mount Vernon, Illinois 62864
Contact:
Site Public Contact
618-242-4600

Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois 61350
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Pekin
Pekin, Illinois 61554
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Pekin, Illinois 61554
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peoria
Peoria, Illinois 61615
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois 61615
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Peoria, Illinois 61636
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

OSF Saint Francis Medical Center
Peoria, Illinois 61637
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Illinois CancerCare-Peru
Peru, Illinois 61354
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Valley Radiation Oncology
Peru, Illinois 61354
Contact:
Site Public Contact
815-664-4141

Illinois CancerCare-Princeton
Princeton, Illinois 61356
Contact:
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com

Southern Illinois University School of Medicine
Springfield, Illinois 62702
Contact:
Site Public Contact
217-545-7929

Springfield Clinic
Springfield, Illinois 62702
Contact:
Site Public Contact
800-444-7541

Memorial Medical Center
Springfield, Illinois 62781
Contact:
Site Public Contact
217-788-3528

Cancer Care Specialists of Illinois-Swansea
Swansea, Illinois 62226
Contact:
Site Public Contact
217-876-4740
rhamrick@dmhhs.org

Southwest Illinois Health Services LLP
Swansea, Illinois 62226
Contact:
Site Public Contact
618-236-1000
lynns@thecancercenter.com

Carle Cancer Center
Urbana, Illinois 61801
Contact:
Site Public Contact
800-446-5532
Research@carle.com

The Carle Foundation Hospital
Urbana, Illinois 61801
Contact:
Site Public Contact
800-446-5532
Research@carle.com

Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois 60555
Contact:
Site Public Contact
630-315-1918
Claudine.Gamster@CadenceHealth.org

Rush-Copley Healthcare Center
Yorkville, Illinois 60560
Contact:
Site Public Contact
630-978-6212
Cancer.Research@rushcopley.com

Franciscan Health Indianapolis
Indianapolis, Indiana 46237
Contact:
Site Public Contact
317-528-7060

Woodland Cancer Care Center
Michigan City, Indiana 46360
Contact:
Site Public Contact
219-861-5800
sally.arnett@franciscanalliance.org

Franciscan Health Mooresville
Mooresville, Indiana 46158
Contact:
Site Public Contact
317-834-3603

Reid Health
Richmond, Indiana 47374
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Union Hospital
Terre Haute, Indiana 47804
Contact:
Site Public Contact
812-238-7394

Mary Greeley Medical Center
Ames, Iowa 50010
Contact:
Site Public Contact
515-956-4132

McFarland Clinic PC - Ames
Ames, Iowa 50010
Contact:
Site Public Contact
515-239-4734
ksoder@mcfarlandclinic.com

McFarland Clinic PC-Boone
Boone, Iowa 50036
Contact:
Site Public Contact
515-956-4132

Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa 50325
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Mercy Cancer Center-West Lakes
Clive, Iowa 50325
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Mercy Hospital
Council Bluffs, Iowa 51503
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Greater Regional Medical Center
Creston, Iowa 50801
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Iowa Methodist Medical Center
Des Moines, Iowa 50309
Contact:
Site Public Contact
515-241-6727

Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa 50309
Contact:
Site Public Contact
515-282-2921

Broadlawns Medical Center
Des Moines, Iowa 50314
Contact:
Site Public Contact
515-282-2200

Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa 50314
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Mercy Medical Center - Des Moines
Des Moines, Iowa 50314
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Iowa Lutheran Hospital
Des Moines, Iowa 50316
Contact:
Site Public Contact
515-241-8704

McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa 50501
Contact:
Site Public Contact
515-956-4132

Trinity Regional Medical Center
Fort Dodge, Iowa 50501
Contact:
Site Public Contact
515-574-8302

McFarland Clinic PC-Jefferson
Jefferson, Iowa 50129
Contact:
Site Public Contact
515-956-4132

McFarland Clinic PC-Marshalltown
Marshalltown, Iowa 50158
Contact:
Site Public Contact
515-956-4132

Siouxland Regional Cancer Center
Sioux City, Iowa 51101
Contact:
Site Public Contact
712-252-9326
HoopingarnerT@jencc.com

Methodist West Hospital
West Des Moines, Iowa 50266-7700
Contact:
Site Public Contact
515-343-1000

Mercy Medical Center-West Lakes
West Des Moines, Iowa 50266
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Lawrence Memorial Hospital
Lawrence, Kansas 66044
Contact:
Site Public Contact
316-268-5374
Keisha.humphries@ascension.org

Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas 67208
Contact:
Site Public Contact
316-268-5374
Keisha.humphries@ascension.org

Cancer Center of Kansas - Wichita
Wichita, Kansas 67214
Contact:
Site Public Contact
316-268-5374
Keisha.humphries@ascension.org

Flaget Memorial Hospital
Bardstown, Kentucky 40004
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Commonwealth Cancer Center-Corbin
Corbin, Kentucky 40701
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky 40504
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Joseph Hospital East
Lexington, Kentucky 40509
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Joseph London
London, Kentucky 40741
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Jewish Hospital
Louisville, Kentucky 40202
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky 40202
Contact:
Site Public Contact
502-562-3429

Saints Mary and Elizabeth Hospital
Louisville, Kentucky 40215
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Jewish Hospital Medical Center Northeast
Louisville, Kentucky 40245
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Jewish Hospital Medical Center South
Shepherdsville, Kentucky 40165
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

LSU Health Baton Rouge-North Clinic
Baton Rouge, Louisiana 70805
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana 70809
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana 70809
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Our Lady of the Lake Physicians Group - Medical Oncology
Baton Rouge, Louisiana 70809
Contact:
Site Public Contact
225-215-1353
clinicalresearch@marybird.com

Louisiana State University Health Science Center
New Orleans, Louisiana 70112
Contact:
Site Public Contact
504-210-3539
emede1@lsuhsc.edu

Harold Alfond Center for Cancer Care
Augusta, Maine 04330
Contact:
Site Public Contact
207-626-4855

Eastern Maine Medical Center
Bangor, Maine 04401
Contact:
Site Public Contact
207-973-4274

Waldo County General Hospital
Belfast, Maine 04915
Contact:
Site Public Contact
207-338-2500

MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford
Biddeford, Maine 04005
Contact:
Site Public Contact
LLemire@mmc.org

Lafayette Family Cancer Center-EMMC
Brewer, Maine 04412
Contact:
Site Public Contact
800-987-3005

Stephens Memorial Hospital
Norway, Maine 04268
Contact:
Site Public Contact
207-396-8670
OncClinicalResearch@mmc.org

Penobscot Bay Medical Center
Rockport, Maine 04856
Contact:
Site Public Contact
207-396-8670
ClinicalResearch@mmc.org

MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford
Sanford, Maine 04073
Contact:
Site Public Contact
LLemire@mmc.org

Maine Medical Partners - South Portland
South Portland, Maine 04106
Contact:
Site Public Contact
207-396-8670
ClinicalResearch@mmc.org

Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland 21287
Contact:
Site Public Contact
410-955-8804
jhcccro@jhmi.edu

Beth Israel Deaconess Medical Center
Boston, Massachusetts 02215
Contact:
Site Public Contact
617-667-9925

Dana-Farber Cancer Institute
Boston, Massachusetts 02215
Contact:
Site Public Contact
877-442-3324

Lowell General Hospital
Lowell, Massachusetts 01854
Contact:
Site Public Contact
978-788-7084
ghincks@lowellgeneral.org

UMass Memorial Medical Center - University Campus
Worcester, Massachusetts 01655
Contact:
Site Public Contact
508-856-3216
cancer.research@umassmed.edu

University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan 48109
Contact:
Site Public Contact
800-865-1125

Bronson Battle Creek
Battle Creek, Michigan 49017
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

McLaren Cancer Institute-Bay City
Bay City, Michigan 48706
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Clarkston
Clarkston, Michigan 48346
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Wayne State University/Karmanos Cancer Institute
Detroit, Michigan 48201
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Weisberg Cancer Treatment Center
Farmington Hills, Michigan 48334
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Flint
Flint, Michigan 48532
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Singh and Arora Hematology Oncology PC
Flint, Michigan 48532
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan 49503
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Mercy Health Saint Mary's
Grand Rapids, Michigan 49503
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Spectrum Health at Butterworth Campus
Grand Rapids, Michigan 49503
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Bronson Methodist Hospital
Kalamazoo, Michigan 49007
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

West Michigan Cancer Center
Kalamazoo, Michigan 49007
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Borgess Medical Center
Kalamazoo, Michigan 49048
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

McLaren-Greater Lansing
Lansing, Michigan 48910
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Mid-Michigan Physicians-Lansing
Lansing, Michigan 48912
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Lapeer Region
Lapeer, Michigan 48446
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Macomb
Mount Clemens, Michigan 48043
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

McLaren Cancer Institute-Central Michigan
Mount Pleasant, Michigan 48858
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Mercy Health Mercy Campus
Muskegon, Michigan 49444
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Lakeland Hospital Niles
Niles, Michigan 49120
Contact:
Site Public Contact
616-391-1230

Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan 49444
Contact:
Site Public Contact
616-391-1230
connie.szczepanek@crcwm.org

McLaren-Port Huron
Port Huron, Michigan 48060
Contact:
Site Public Contact
313-576-9790
ctoadmin@karmanos.org

Spectrum Health Reed City Hospital
Reed City, Michigan 49677
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Lakeland Medical Center Saint Joseph
Saint Joseph, Michigan 49085
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Marie Yeager Cancer Center
Saint Joseph, Michigan 49085
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Munson Medical Center
Traverse City, Michigan 49684
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Metro Health Hospital
Wyoming, Michigan 49519
Contact:
Site Public Contact
616-391-1230
crcwm-regulatory@crcwm.org

Riverwood Healthcare Center
Aitkin, Minnesota 56431
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Sanford Joe Lueken Cancer Center
Bemidji, Minnesota 56601
Contact:
Site Public Contact
218-333-5000
OncologyClinicalTrialsFargo@sanfordhealth.org

Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota 56401
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Fairview Ridges Hospital
Burnsville, Minnesota 55337
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Cambridge Medical Center
Cambridge, Minnesota 55008
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mercy Hospital
Coon Rapids, Minnesota 55433
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Deer River Clinic
Deer River, Minnesota 56636
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota 56501
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Cancer Center
Duluth, Minnesota 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's Medical Center
Duluth, Minnesota 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Miller-Dwan Hospital
Duluth, Minnesota 55805
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Fairview-Southdale Hospital
Edina, Minnesota 55435
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Lake Region Healthcare Corporation-Cancer Care
Fergus Falls, Minnesota 56537
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Essentia Health - Fosston
Fosston, Minnesota 56542
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Unity Hospital
Fridley, Minnesota 55432
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health Hibbing Clinic
Hibbing, Minnesota 55746
Contact:
Site Public Contact
218-786-3308

Fairview Maple Grove Medical Center
Maple Grove, Minnesota 55369
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota 55109
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Maplewood, Minnesota 55109
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Abbott-Northwestern Hospital
Minneapolis, Minnesota 55407
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Hennepin County Medical Center
Minneapolis, Minnesota 55415
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Health Partners Inc
Minneapolis, Minnesota 55454
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Monticello Cancer Center
Monticello, Minnesota 55362
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

New Ulm Medical Center
New Ulm, Minnesota 56073
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health - Park Rapids
Park Rapids, Minnesota 56470
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Fairview Northland Medical Center
Princeton, Minnesota 55371
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

North Memorial Medical Health Center
Robbinsdale, Minnesota 55422
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Mayo Clinic
Rochester, Minnesota 55905
Contact:
Site Public Contact
855-776-0015

Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota 55416
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Regions Hospital
Saint Paul, Minnesota 55101
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

United Hospital
Saint Paul, Minnesota 55102
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Essentia Health Sandstone
Sandstone, Minnesota 55072
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Saint Francis Regional Medical Center
Shakopee, Minnesota 55379
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Lakeview Hospital
Stillwater, Minnesota 55082
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Sanford Thief River Falls Medical Center
Thief River Falls, Minnesota 56701
Contact:
Site Public Contact
605-312-3320

Essentia Health Virginia Clinic
Virginia, Minnesota 55792
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Ridgeview Medical Center
Waconia, Minnesota 55387
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Rice Memorial Hospital
Willmar, Minnesota 56201
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota 55125
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Sanford Cancer Center Worthington
Worthington, Minnesota 56187
Contact:
Site Public Contact
605-312-3320

Fairview Lakes Medical Center
Wyoming, Minnesota 55092
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus, Mississippi 39705
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Baptist Cancer Center-Grenada
Grenada, Mississippi 38901
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Gulfport Memorial Hospital
Gulfport, Mississippi 39502
Contact:
Site Public Contact
504-210-3539
emede1@lsuhsc.edu

Baptist Memorial Hospital and Cancer Center-Union County
New Albany, Mississippi 38652
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi 38655
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven, Mississippi 38671
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri 63011
Contact:
Site Public Contact
314-251-7058

Parkland Health Center-Bonne Terre
Bonne Terre, Missouri 63628
Contact:
Site Public Contact
314-996-5569

Cox Cancer Center Branson
Branson, Missouri 65616
Contact:
Site Public Contact
417-269-4520

Saint Francis Medical Center
Cape Girardeau, Missouri 63703
Contact:
Site Public Contact
573-334-2230
sfmc@sfmc.net

Southeast Cancer Center
Cape Girardeau, Missouri 63703
Contact:
Site Public Contact
573-651-5550

Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri 63141
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Parkland Health Center - Farmington
Farmington, Missouri 63640
Contact:
Site Public Contact
314-996-5569

Capital Region Southwest Campus
Jefferson City, Missouri 65109
Contact:
Site Public Contact
573-632-4814
swooden@mail.crmc.org

Freeman Health System
Joplin, Missouri 64804
Contact:
Site Public Contact
417-347-4030
LJCrockett@freemanhealth.com

Mercy Hospital Joplin
Joplin, Missouri 64804
Contact:
Site Public Contact
417-556-3074
esmeralda.carrillo@mercy.net

Delbert Day Cancer Institute at PCRMC
Rolla, Missouri 65401
Contact:
Site Public Contact
573-458-7504
jrichards@research.pcrmc.com

Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri 65401
Contact:
Site Public Contact
573-458-7504
jrichards@research.pcrmc.com

Heartland Regional Medical Center
Saint Joseph, Missouri 64507
Contact:
Site Public Contact
816-271-7937
linda.schumacher@mymlc.com

Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri 63109
Contact:
Site Public Contact
314-353-1870

Washington University School of Medicine
Saint Louis, Missouri 63110
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Mercy Hospital South
Saint Louis, Missouri 63128
Contact:
Site Public Contact
janet.lesko@mercy.net

Siteman Cancer Center-South County
Saint Louis, Missouri 63129
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Missouri Baptist Medical Center
Saint Louis, Missouri 63131
Contact:
Site Public Contact
314-996-5569

Siteman Cancer Center at Christian Hospital
Saint Louis, Missouri 63136
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Mercy Hospital Saint Louis
Saint Louis, Missouri 63141
Contact:
Site Public Contact
314-251-7066

Siteman Cancer Center at Saint Peters Hospital
Saint Peters, Missouri 63376
Contact:
Site Public Contact
800-600-3606
info@siteman.wustl.edu

Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri 63670
Contact:
Site Public Contact
314-996-5569

Mercy Hospital Springfield
Springfield, Missouri 65804
Contact:
Site Public Contact
417-269-4520

CoxHealth South Hospital
Springfield, Missouri 65807
Contact:
Site Public Contact
417-269-4520

Missouri Baptist Sullivan Hospital
Sullivan, Missouri 63080
Contact:
Site Public Contact
314-996-5569

Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, Missouri 63127
Contact:
Site Public Contact
314-996-5569

Mercy Hospital Washington
Washington, Missouri 63090
Contact:
Site Public Contact
636-390-1600

Community Hospital of Anaconda
Anaconda, Montana 59711
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Billings Clinic Cancer Center
Billings, Montana 59101
Contact:
Site Public Contact
800-996-2663
research@billingsclinic.org

Bozeman Deaconess Hospital
Bozeman, Montana 59715
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana 59405
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Great Falls Clinic
Great Falls, Montana 59405
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Kalispell Regional Medical Center
Kalispell, Montana 59901
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

Saint Patrick Hospital - Community Hospital
Missoula, Montana 59802
Contact:
Site Public Contact
406-327-3118
amy.hanneman@providence.org

Community Medical Hospital
Missoula, Montana 59804
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

CHI Health Saint Francis
Grand Island, Nebraska 68803
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

CHI Health Good Samaritan
Kearney, Nebraska 68847
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Saint Elizabeth Regional Medical Center
Lincoln, Nebraska 68510
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Nebraska Methodist Hospital
Omaha, Nebraska 68114
Contact:
Site Public Contact
402-354-5144

Alegent Health Immanuel Medical Center
Omaha, Nebraska 68122
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska 68124
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Alegent Health Lakeside Hospital
Omaha, Nebraska 68130
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Creighton University Medical Center
Omaha, Nebraska 68131
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Midlands Community Hospital
Papillion, Nebraska 68046
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Carson Tahoe Regional Medical Center
Carson City, Nevada 89703
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Cancer and Blood Specialists-Henderson
Henderson, Nevada 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada-Horizon Ridge
Henderson, Nevada 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Cancer Center-Henderson
Henderson, Nevada 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

OptumCare Cancer Care at Seven Hills
Henderson, Nevada 89052
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

21st Century Oncology-Henderson
Henderson, Nevada 89074
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson, Nevada 89074
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Urology - Green Valley
Henderson, Nevada 89074
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Pebble
Henderson, Nevada 89074
Contact:
Site Public Contact
research@sncrf.org

Urology Specialists of Nevada - Green Valley
Henderson, Nevada 89074
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Pecos
Las Vegas, Nevada 89074
Contact:
Site Public Contact
research@sncrf.org

Desert West Surgery
Las Vegas, Nevada 89102
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

University Medical Center of Southern Nevada
Las Vegas, Nevada 89102
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Hope Cancer Care of Nevada
Las Vegas, Nevada 89103
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Cancer and Blood Specialists-Shadow
Las Vegas, Nevada 89106
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

OptumCare Cancer Care at Oakey
Las Vegas, Nevada 89106
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada 89106
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Urology Specialists of Nevada - Central
Las Vegas, Nevada 89106
Contact:
Site Public Contact
research@sncrf.org

21st Century Oncology
Las Vegas, Nevada 89109
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
Las Vegas, Nevada 89109
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Sunrise Hospital and Medical Center
Las Vegas, Nevada 89109
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-San Martin
Las Vegas, Nevada 89113
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Prostate Cancer Center
Las Vegas, Nevada 89113
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Sunset
Las Vegas, Nevada 89113
Contact:
Site Public Contact
research@sncrf.org

Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada 89119
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

21st Century Oncology-Vegas Tenaya
Las Vegas, Nevada 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Ann M Wierman MD LTD
Las Vegas, Nevada 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Cancer and Blood Specialists-Tenaya
Las Vegas, Nevada 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-Tenaya
Las Vegas, Nevada 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Urology - Cathedral Rock
Las Vegas, Nevada 89128
Contact:
Site Public Contact
research@sncrf.org

Las Vegas Urology - Smoke Ranch
Las Vegas, Nevada 89128
Contact:
Site Public Contact
research@smcrf.org

OptumCare Cancer Care at MountainView
Las Vegas, Nevada 89128
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Urology Specialists of Nevada - Northwest
Las Vegas, Nevada 89128
Contact:
Site Public Contact
research@sncrf.org

Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada 89135
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas, Nevada 89144
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas, Nevada 89144
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Summerlin Hospital Medical Center
Las Vegas, Nevada 89144
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Las Vegas Cancer Center-Medical Center
Las Vegas, Nevada 89148-2405
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

21st Century Oncology-Fort Apache
Las Vegas, Nevada 89148
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada 89148
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada 89148
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Urology Specialists of Nevada - Southwest
Las Vegas, Nevada 89148
Contact:
Site Public Contact
research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
Las Vegas, Nevada 89149
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada 89169
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

University Cancer Center
Las Vegas, Nevada 89169
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Hope Cancer Care of Nevada-Pahrump
Pahrump, Nevada 89048
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Renown Regional Medical Center
Reno, Nevada 89502
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Saint Mary's Regional Medical Center
Reno, Nevada 89503
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Radiation Oncology Associates
Reno, Nevada 89509
Contact:
Site Public Contact
702-384-0013
research@sncrf.org

Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire 03756
Contact:
Site Public Contact
800-639-6918
cancer.research.nurse@dartmouth.edu

Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey 08903
Contact:
Site Public Contact
732-235-8675

Holy Name Hospital
Teaneck, New Jersey 07666
Contact:
Site Public Contact
201-833-6312

Lovelace Medical Center-Saint Joseph Square
Albuquerque, New Mexico 87102
Contact:
Site Public Contact
505-272-0530
AYost@nmcca.org

University of New Mexico Cancer Center
Albuquerque, New Mexico 87102
Contact:
Site Public Contact
505-925-0366
LByatt@nmcca.org

New Mexico Oncology Hematology Consultants
Albuquerque, New Mexico 87109
Contact:
Site Public Contact
505-272-0530
CLee@nmcca.org

Presbyterian Kaseman Hospital
Albuquerque, New Mexico 87110
Contact:
Site Public Contact
505-559-6113
WBurman@phs.org

Memorial Medical Center - Las Cruces
Las Cruces, New Mexico 88011
Contact:
Site Public Contact
575-556-6545
Kim.Hoffman@lpnt.net

Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho, New Mexico 87124
Contact:
Site Public Contact
505-559-6113
WBurman@phs.org

Roswell Park Cancer Institute
Buffalo, New York 14263
Contact:
Site Public Contact
800-767-9355
askroswell@roswellpark.org

Glens Falls Hospital
Glens Falls, New York 12801
Contact:
Site Public Contact
518-926-6700

NYP/Weill Cornell Medical Center
New York, New York 10065
Contact:
Site Public Contact
212-746-1848

University of Rochester
Rochester, New York 14642
Contact:
Site Public Contact
585-275-5830

Stony Brook University Medical Center
Stony Brook, New York 11794
Contact:
Site Public Contact
800-862-2215

Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina 28328
Contact:
Site Public Contact
919-587-9077
ecooke@cancersmoc.com

Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina 27534
Contact:
Site Public Contact
919-587-9077
ecooke@cancersmoc.com

Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina 28791
Contact:
Site Public Contact
828-696-4716
karen.morris@unchealth.unc.edu

Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina 28546
Contact:
Site Public Contact
910-353-0824
ecooke@cancersmoc.com

Vidant Oncology-Kenansville
Kenansville, North Carolina 28349
Contact:
Site Public Contact
252-559-2201
Carla.Zimmerman@vidanthealth.com

Vidant Oncology-Kinston
Kinston, North Carolina 28501
Contact:
Site Public Contact
252-559-2201
Carla.Zimmerman@vidanthealth.com

Vidant Oncology-Richlands
Richlands, North Carolina 28574
Contact:
Site Public Contact
252-559-2201
Carla.Zimmerman@vidanthealth.com

Sanford Bismarck Medical Center
Bismarck, North Dakota 58501
Contact:
Site Public Contact
701-323-5760
OncologyClinicalTrialsFargo@sanfordhealth.org

Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota 58103
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Sanford South University Medical Center
Fargo, North Dakota 58103
Contact:
Site Public Contact
701-234-6161

Sanford Medical Center Fargo
Fargo, North Dakota 58104
Contact:
Site Public Contact
800-437-4010

Sanford Broadway Medical Center
Fargo, North Dakota 58122
Contact:
Site Public Contact
701-323-5760
OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford Roger Maris Cancer Center
Fargo, North Dakota 58122
Contact:
Site Public Contact
701-234-6161
OncologyClinicalTrialsFargo@sanfordhealth.org

Essentia Health - Jamestown Clinic
Jamestown, North Dakota 58401
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio 44122
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Indu and Raj Soin Medical Center
Beavercreek, Ohio 45431
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Strecker Cancer Center-Belpre
Belpre, Ohio 45714
Contact:
Site Public Contact
800-523-3977
sheree@columbusccop.org

Saint Elizabeth Boardman Hospital
Boardman, Ohio 44512
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Mercy Medical Center
Canton, Ohio 44708
Contact:
Site Public Contact
888-293-4673

Dayton Physicians LLC-Miami Valley South
Centerville, Ohio 45459
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Miami Valley Hospital South
Centerville, Ohio 45459
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Geauga Hospital
Chardon, Ohio 44024
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Adena Regional Medical Center
Chillicothe, Ohio 45601
Contact:
Site Public Contact
877-779-7585
sheree@columbusccop.org

University of Cincinnati/Barrett Cancer Center
Cincinnati, Ohio 45219
Contact:
Site Public Contact
513-558-4553
uchealthnews@uc.edu

Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio 45220
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio 45236
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Bethesda North Hospital
Cincinnati, Ohio 45242
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

TriHealth Cancer Institute-Westside
Cincinnati, Ohio 45247
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

TriHealth Cancer Institute-Anderson
Cincinnati, Ohio 45255
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Case Western Reserve University
Cleveland, Ohio 44106
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

MetroHealth Medical Center
Cleveland, Ohio 44109
Contact:
Site Public Contact
216-778-8526
dstrater@metrohealth.org

Mount Carmel East Hospital
Columbus, Ohio 43213
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Columbus Oncology and Hematology Associates Inc
Columbus, Ohio 43214
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Riverside Methodist Hospital
Columbus, Ohio 43214
Contact:
Site Public Contact
614-566-4475
sheree@columbusccop.org

Grant Medical Center
Columbus, Ohio 43215
Contact:
Site Public Contact
614-566-4475
sheree@columbusccop.org

The Mark H Zangmeister Center
Columbus, Ohio 43219
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

Mount Carmel Health Center West
Columbus, Ohio 43222
Contact:
Site Public Contact
614-234-5433
sheree@columbusccop.org

Doctors Hospital
Columbus, Ohio 43228
Contact:
Site Public Contact
614-566-3275
sheree@columbusccop.org

Miami Valley Hospital
Dayton, Ohio 45409
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Dayton Physician LLC-Miami Valley Hospital North
Dayton, Ohio 45415
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Delaware Health Center-Grady Cancer Center
Delaware, Ohio 43015
Contact:
Site Public Contact
740-615-0227
sheree@columbusccop.org

Grady Memorial Hospital
Delaware, Ohio 43015
Contact:
Site Public Contact
740-615-2403
sheree@columbusccop.org

Dublin Methodist Hospital
Dublin, Ohio 43016
Contact:
Site Public Contact
800-752-9119
sheree@columbusccop.org

Mercy Cancer Center-Elyria
Elyria, Ohio 44035
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Armes Family Cancer Center
Findlay, Ohio 45840
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Blanchard Valley Hospital
Findlay, Ohio 45840
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Orion Cancer Care
Findlay, Ohio 45840
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio 45005-1066
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Dayton Physicians LLC-Atrium
Franklin, Ohio 45005
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Central Ohio Breast and Endocrine Surgery
Gahanna, Ohio 43230
Contact:
Site Public Contact
614-488-2745
sheree@columbusccop.org

Dayton Physicians LLC-Wayne
Greenville, Ohio 45331
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Wayne Hospital
Greenville, Ohio 45331
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Greater Dayton Cancer Center
Kettering, Ohio 45409
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

First Dayton Cancer Care
Kettering, Ohio 45420
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Kettering Medical Center
Kettering, Ohio 45429
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Fairfield Medical Center
Lancaster, Ohio 43130
Contact:
Site Public Contact
740-687-8863
sheree@columbusccop.org

OhioHealth Mansfield Hospital
Mansfield, Ohio 44903
Contact:
Site Public Contact
419-526-8018
sheree@columbusccop.org

Marietta Memorial Hospital
Marietta, Ohio 45750
Contact:
Site Public Contact
800-523-3977
sheree@columbusccop.org

OhioHealth Marion General Hospital
Marion, Ohio 43302
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

UH Seidman Cancer Center at Landerbrook Health Center
Mayfield Heights, Ohio 44124
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio 44060
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

UH Seidman Cancer Center at Southwest General Hospital
Middleburg Heights, Ohio 44130
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Knox Community Hospital
Mount Vernon, Ohio 43050
Contact:
Site Public Contact
740-393-9000
sheree@columbusccop.org

Licking Memorial Hospital
Newark, Ohio 43055
Contact:
Site Public Contact
740-348-4000
sheree@columbusccop.org

Newark Radiation Oncology
Newark, Ohio 43055
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

University Hospitals Parma Medical Center
Parma, Ohio 44129
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Southern Ohio Medical Center
Portsmouth, Ohio 45662
Contact:
Site Public Contact
614-488-2118
sheree@columbusccop.org

University Hospitals Portage Medical Center
Ravenna, Ohio 44266
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

UH Seidman Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio 44870
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Springfield Regional Cancer Center
Springfield, Ohio 45504
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Springfield Regional Medical Center
Springfield, Ohio 45505
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Dayton Physicians LLC-Upper Valley
Troy, Ohio 45373
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Upper Valley Medical Center
Troy, Ohio 45373
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

University Hospitals Sharon Health Center
Wadsworth, Ohio 44281
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Saint Joseph Warren Hospital
Warren, Ohio 44484
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

University Pointe
West Chester, Ohio 45069
Contact:
Site Public Contact
clinicaltrials@ucphysicians.com

Saint Ann's Hospital
Westerville, Ohio 43081
Contact:
Site Public Contact
614-234-5433
sheree@columbusccop.org

UH Seidman Cancer Center at Saint John Medical Center
Westlake, Ohio 44145
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

UHHS-Westlake Medical Center
Westlake, Ohio 44145
Contact:
Site Public Contact
800-641-2422
CTUReferral@UHhospitals.org

Saint Elizabeth Youngstown Hospital
Youngstown, Ohio 44501
Contact:
Site Public Contact
937-775-1350
som_dcop@wright.edu

Genesis Healthcare System Cancer Care Center
Zanesville, Ohio 43701
Contact:
Site Public Contact
740-454-5232
sheree@columbusccop.org

Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma 73505
Contact:
Site Public Contact
877-231-4440

University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma 73104
Contact:
Site Public Contact
405-271-8777
ou-clinical-trials@ouhsc.edu

Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma 73120
Contact:
Site Public Contact
405-752-3402

Cancer Treatment Centers of America
Tulsa, Oklahoma 74133
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma 74146
Contact:
Site Public Contact
918-505-3200

Saint Alphonsus Medical Center-Baker City
Baker City, Oregon 97814
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Saint Charles Health System
Bend, Oregon 97701
Contact:
Site Public Contact
541-706-2909
nosall@stcharleshealthcare.org

Clackamas Radiation Oncology Center
Clackamas, Oregon 97015
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Providence Oncology and Hematology Care Southeast
Clackamas, Oregon 97015
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Bay Area Hospital
Coos Bay, Oregon 97420
Contact:
Site Public Contact
541-269-8392
cherie.cox@bayareahospital.org

Good Samaritan Hospital
Corvallis, Oregon 97330
Contact:
Site Public Contact
541-768-4352
stmock@samhealth.org

Legacy Mount Hood Medical Center
Gresham, Oregon 97030
Contact:
Site Public Contact
503-413-2150

Providence Newberg Medical Center
Newberg, Oregon 97132
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Saint Alphonsus Medical Center-Ontario
Ontario, Oregon 97914
Contact:
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org

Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon 97210
Contact:
Site Public Contact
800-220-4937
cancer@lhs.org

Providence Portland Medical Center
Portland, Oregon 97213
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Providence Saint Vincent Medical Center
Portland, Oregon 97225
Contact:
Site Public Contact
503-215-2614
CanRsrchStudies@providence.org

Oregon Health and Science University
Portland, Oregon 97239
Contact:
Site Public Contact
503-494-1080
trials@ohsu.edu

Saint Charles Health System-Redmond
Redmond, Oregon 97756
Contact:
Site Public Contact
541-706-2909

Legacy Meridian Park Hospital
Tualatin, Oregon 97062
Contact:
Site Public Contact
503-413-1742

Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania 19317
Contact:
Site Public Contact
302-623-4450
KDempsey@christianacare.org

Eastern Regional Medical Center
Philadelphia, Pennsylvania 19124
Contact:
Site Public Contact
888-823-5923
ctsucontact@westat.com

Prisma Health Cancer Institute - Easley
Easley, South Carolina 29640
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Saint Francis Hospital
Greenville, South Carolina 29601
Contact:
Site Public Contact
864-603-6213
meissa_beckman@bshsi.org

Prisma Health Cancer Institute - Butternut
Greenville, South Carolina 29605
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Prisma Health Cancer Institute - Faris
Greenville, South Carolina 29605
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Prisma Health Greenville Memorial Hospital
Greenville, South Carolina 29605
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Saint Francis Cancer Center
Greenville, South Carolina 29607
Contact:
Site Public Contact
864-603-6213
meissa_beckman@bshsi.org

Prisma Health Cancer Institute - Eastside
Greenville, South Carolina 29615
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Prisma Health Cancer Institute - Greer
Greer, South Carolina 29650
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Prisma Health Cancer Institute - Seneca
Seneca, South Carolina 29672
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Prisma Health Cancer Institute - Spartanburg
Spartanburg, South Carolina 29307
Contact:
Site Public Contact
864-522-2066
kim.williams3@prismahealth.org

Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota 57104
Contact:
Site Public Contact
605-312-3320
OncologyClinicTrialsSF@sanfordhealth.org

Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota 57117-5134
Contact:
Site Public Contact
605-312-3320
OncologyClinicalTrialsSF@SanfordHealth.org

Wellmont Bristol Regional Medical Center
Bristol, Tennessee 37620
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Baptist Memorial Hospital and Cancer Center-Collierville
Collierville, Tennessee 38017
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Cookeville Regional Medical Center
Cookeville, Tennessee 38501
Contact:
Site Public Contact
931-783-2714

Vanderbilt-Ingram Cancer Center at Franklin
Franklin, Tennessee 37067
Contact:
Site Public Contact
800-811-8480

Vanderbilt-Ingram Cancer Center Cool Springs
Franklin, Tennessee 37067
Contact:
Site Public Contact
800-811-8480

Regional Cancer Center at Indian Path Community Hospital
Kingsport, Tennessee 37660
Contact:
Site Public Contact
423-578-8538
Justin.reynolds@balladhealth.org

Wellmont Holston Valley Hospital and Medical Center
Kingsport, Tennessee 37660
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee 38120
Contact:
Site Public Contact
901-226-1366
BCCclintrials@bmhcc.org

Vanderbilt Breast Center at One Hundred Oaks
Nashville, Tennessee 37204
Contact:
Site Public Contact
800-811-8480

Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee 37232
Contact:
Site Public Contact
800-811-8480

Saint Joseph Regional Cancer Center
Bryan, Texas 77802
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Parkland Memorial Hospital
Dallas, Texas 75235
Contact:
Site Public Contact
214-590-5582
canceranswerline@UTSouthwestern.edu

UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas 75390
Contact:
Site Public Contact
214-648-7097
canceranswerline@UTSouthwestern.edu

UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, Texas 76104
Contact:
Site Public Contact
214-648-7097
canceranswerline@UTSouthwestern.edu

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas 77030
Contact:
Site Public Contact
713-798-1354
burton@bcm.edu

Ben Taub General Hospital
Houston, Texas 77030
Contact:
Site Public Contact
713-873-2000

M D Anderson Cancer Center
Houston, Texas 77030
Contact:
Site Public Contact
877-632-6789
askmdanderson@mdanderson.org

Michael E DeBakey VA Medical Center
Houston, Texas 77030
Contact:
Site Public Contact
800-553-2278

UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas 75080
Contact:
Site Public Contact
972-669-7044
Suzanne.cole@utsouthwestern.edu

University of Texas Health Science Center at San Antonio
San Antonio, Texas 78229
Contact:
Site Public Contact
210-450-3800
phoresearchoffice@uthscsa.edu

Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah 84112
Contact:
Site Public Contact
888-424-2100
cancerinfo@hci.utah.edu

Central Vermont Medical Center/National Life Cancer Treatment
Berlin, Vermont 05602
Contact:
Site Public Contact
802-225-5400

University of Vermont Medical Center
Burlington, Vermont 05401
Contact:
Site Public Contact
802-656-4101
rpo@uvm.edu

University of Vermont and State Agricultural College
Burlington, Vermont 05405
Contact:
Site Public Contact
802-656-8990
rpo@uvm.edu

Wellmont Medical Associates-Bristol
Bristol, Virginia 24201
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Southwest VA Regional Cancer Center
Norton, Virginia 24273
Contact:
Site Public Contact
423-578-8538
justin.reynolds@wellmont.org

Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia 23298
Contact:
Site Public Contact
804-628-1914
klcampbell@vcu.edu

Providence Regional Cancer System-Aberdeen
Aberdeen, Washington 98520
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Overlake Hospital Medical Center
Bellevue, Washington 98004
Contact:
Site Public Contact
425-688-5407
OHMCResearch@overlakehospital.org

PeaceHealth Saint Joseph Medical Center
Bellingham, Washington 98225
Contact:
Site Public Contact
360-715-4133
mjohnson9@peacehealth.org

Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington 98310
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Harrison Medical Center
Bremerton, Washington 98310
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Highline Medical Center-Main Campus
Burien, Washington 98166
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Providence Regional Cancer System-Centralia
Centralia, Washington 98531
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Swedish Cancer Institute-Edmonds
Edmonds, Washington 98026
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Saint Elizabeth Hospital
Enumclaw, Washington 98022
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Providence Regional Cancer Partnership
Everett, Washington 98201
Contact:
Site Public Contact
425-261-3529
marilyn.birchman@providence.org

Saint Francis Hospital
Federal Way, Washington 98003
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Swedish Cancer Institute-Issaquah
Issaquah, Washington 98029
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Kadlec Clinic Hematology and Oncology
Kennewick, Washington 99336
Contact:
Site Public Contact
509-783-4637
research@kadlecmed.org

Providence Regional Cancer System-Lacey
Lacey, Washington 98503
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Saint Clare Hospital
Lakewood, Washington 98499
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

PeaceHealth Saint John Medical Center
Longview, Washington 98632
Contact:
Site Public Contact
360-514-2016
kmakin-bond@peacehealth.org

Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, Washington 98370
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

Valley Medical Center
Renton, Washington 98055
Contact:
Site Public Contact
425-228-3440
research@valleymed.org

Pacific Gynecology Specialists
Seattle, Washington 98104
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-Ballard Campus
Seattle, Washington 98107
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-First Hill
Seattle, Washington 98122-4307
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

Swedish Medical Center-Cherry Hill
Seattle, Washington 98122-5711
Contact:
Site Public Contact
206-215-3086
PCRC-NCORP@Swedish.org

PeaceHealth United General Medical Center
Sedro-Woolley, Washington 98284
Contact:
Site Public Contact
360-788-8240

Providence Regional Cancer System-Shelton
Shelton, Washington 98584
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Franciscan Research Center-Northwest Medical Plaza
Tacoma, Washington 98405
Contact:
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org

PeaceHealth Southwest Medical Center
Vancouver, Washington 98664
Contact:
Site Public Contact
360-514-3940
kmakin-bond@peacehealth.org

Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington 98684
Contact:
Site Public Contact
oncologyresearch@lhs.org

Legacy Salmon Creek Hospital
Vancouver, Washington 98686
Contact:
Site Public Contact
503-413-2150

Providence Saint Mary Regional Cancer Center
Walla Walla, Washington 99362
Contact:
Site Public Contact
509-897-5993
Cheryl.Dodd@providence.org

Providence Regional Cancer System-Yelm
Yelm, Washington 98597
Contact:
Site Public Contact
360-412-8958
deidre.dillon@providence.org

Duluth Clinic Ashland
Ashland, Wisconsin 54806
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Northwest Wisconsin Cancer Center
Ashland, Wisconsin 54806
Contact:
Site Public Contact
218-786-3308
CancerTrials@EssentiaHealth.org

Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin 53105
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin 54729
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin 54701
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin 54701
Contact:
Site Public Contact
855-776-0015

Aurora Health Center-Fond du Lac
Fond Du Lac, Wisconsin 54937
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Health Care Germantown Health Center
Germantown, Wisconsin 53022
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Cancer Care-Grafton
Grafton, Wisconsin 53024
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora BayCare Medical Center
Green Bay, Wisconsin 54311
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin 53142
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Gundersen Lutheran Medical Center
La Crosse, Wisconsin 54601
Contact:
Site Public Contact
608-775-2385
cancerctr@gundersenhealth.org

Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin 54601
Contact:
Site Public Contact
855-776-0015

Marshfield Clinic - Ladysmith Center
Ladysmith, Wisconsin 54848
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

University of Wisconsin Hospital and Clinics
Madison, Wisconsin 53792
Contact:
Site Public Contact
800-622-8922

Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin 54143
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Medical Center-Marshfield
Marshfield, Wisconsin 54449
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin 53209
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin 53215
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Sinai Medical Center
Milwaukee, Wisconsin 53233
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin 54548
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

ProHealth D N Greenwald Center
Mukwonago, Wisconsin 53149
Contact:
Site Public Contact
research.institute@phci.org

Cancer Center of Western Wisconsin
New Richmond, Wisconsin 54017
Contact:
Site Public Contact
952-993-1517
mmcorc@healthpartners.com

ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin 53066
Contact:
Site Public Contact
262-928-7878

Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin 54904
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora Cancer Care-Racine
Racine, Wisconsin 53406
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin 54868
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin 53081
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Clinic Stevens Point Center
Stevens Point, Wisconsin 54482
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Medical Center in Summit
Summit, Wisconsin 53066
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin 54241
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin 53188
Contact:
Site Public Contact
262-928-7632

UW Cancer Center at ProHealth Care
Waukesha, Wisconsin 53188
Contact:
Site Public Contact
262-928-5539
Chanda.miller@phci.org

Marshfield Clinic-Wausau Center
Wausau, Wisconsin 54401
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin 53226
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Aurora West Allis Medical Center
West Allis, Wisconsin 53227
Contact:
Site Public Contact
414-302-2304
ncorp@aurora.org

Marshfield Clinic - Weston Center
Weston, Wisconsin 54476
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin 54494
Contact:
Site Public Contact
800-782-8581
oncology.clinical.trials@marshfieldresearch.org

Billings Clinic-Cody
Cody, Wyoming 82414
Contact:
Site Public Contact
800-996-2663
research@billingsclinic.org

Welch Cancer Center
Sheridan, Wyoming 82801
Contact:
Site Public Contact
406-969-6060
mccinfo@mtcancer.org

More Details

NCT ID
NCT03768414
Status
Recruiting
Sponsor
Southwest Oncology Group

Study Contact

Danae Campos
210-614-8808
dcampos@swog.org

Detailed Description

PRIMARY OBJECTIVES:

I. To compare overall survival (OS) in patients with untreated, advanced biliary cancers treated with gemcitabine hydrochloride (gemcitabine) and cisplatin (GC) versus those treated with gemcitabine, cisplatin, and nab-Paclitaxel (GCN).

SECONDARY OBJECTIVES:

I. To compare progression-free survival (PFS) in patients treated with GC versus GCN.

II. To compare overall response rate (ORR), complete and partial, confirmed and unconfirmed, in the subset of patients with measurable disease treated with GC versus GCN.

III. To compare disease control rate (confirmed and unconfirmed; complete response + partial response + stable disease) (DCR) in patients treated with GC versus GCN.

IV. To evaluate the frequency and severity of toxicity associated with GC and GCN in the patient population.

V. To explore the correlation between change in cancer antigen 19-9 (CA19-9) levels from baseline to post-treatment (after 3 cycles) and overall response rate, in each treatment arm separately and in the total cohort.

ADDITIONAL OBJECTIVES:

I. To bank tissue and blood for future translational medicine studies.

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM I: Patients receive nab-paclitaxel intravenously (IV) over 30 minutes, cisplatin IV over 60 minutes, and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive cisplatin IV over 60 minutes and gemcitabine hydrochloride IV over 30 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 6 months for 2 years and then at the end of year 3.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.